DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and Klk13

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001163876.1	Gene:	Klk13 / 292848	RGDID:	1309337	Length:	276	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	75/280 - (26%)
Similarity:	116/280 - (41%)	Gaps:	45/280 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ISTILVFLLILVQGRS---ISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGAS 64
            ::||....|.|..|.|   ...|:..:|..|.:.||.....:..|:|..|.:..    ...||..
  Rat     5 VATIACLTLALSGGISRDYPKILNGTNGTSGFLPGGYTCLPHSQPWQAALLVRG----RLLCGGV 65

  Fly    65 LISDRYLLTAAHCVEKAVAITYYLGGVLRLAPRQLIRSTNPEVHL-------HPDWNCQ----SL 118
            |:..:::||||||.:.        |..:.|....|.|..|.|..:       ||::...    :.
  Rat    66 LVHPKWVLTAAHCRKD--------GYTVHLGKHALGRVENGEQAMEVVRSIPHPEYQVSPTHLNH 122

  Fly   119 ENDIALVRLPEDALLCDSIRPIRLPGLSSSRNSYDYVP----AIASGWGRMNDESTAISDNLRYV 179
            ::||.|:.|.....|.:.:|.::|       ::.|.:|    ...||||............|:..
  Rat   123 DHDIMLLELKSPVQLSNHVRTLQL-------SADDCLPTGTCCRVSGWGTTTSPQVNYPKTLQCA 180

  Fly   180 YRFVESNEDCEYSY-ANIKPTNICMDT-TGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKS 242
            ...:.|:|:|...| ..|....:|..| .|||.:|.|||||||:.:..      |.|:.|:|...
  Rat   181 NIELRSDEECRQVYPGKITANMLCAGTKEGGKDSCEGDSGGPLICNGK------LYGIISWGDFP 239

  Fly   243 GCTKGYPSVFTRITAYLDWI 262
            ......|.|:||::.||.||
  Rat   240 CGQPNRPGVYTRVSKYLRWI 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	64/247 (26%)
Klk13	NP_001163876.1	Tryp_SPc	39..262	CDD:238113	66/246 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920