DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon74E and Klk6

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_062048.1	Gene:	Klk6 / 29245	RGDID:	3419	Length:	251	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	72/271 - (26%)
Similarity:	115/271 - (42%)	Gaps:	40/271 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TILVFLLILVQGRSISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDR 69
            |:....|.|:..:|....|.     .::..|.....|..|:|..|.    ...:..||..|:..:
  Rat     7 TVKTLALCLILAKSAWSEDQ-----DKVVHGGPCLKNSHPFQAALY----TSGHLLCGGVLVGPQ 62

  Fly    70 YLLTAAHCVEKAVAITYYLGGVLRLAPRQLIRSTN--------PEVHLHPDWNCQSLENDIALVR 126
            ::||||||  |...:..|||       :..:|.|.        ....:||.:|.|:.:|||.:|.
  Rat    63 WVLTAAHC--KKPNLEVYLG-------KHNLRQTETFQRQISVDRTIVHPRYNPQTHDNDIMMVH 118

  Fly   127 LPEDALLCDSIRPIRLPGLSSSRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDCEY 191
            |.........|:|:.|....|.:|....:    .|||:|  |:....|.::.....:.|.|:||.
  Rat   119 LKRPVKFSQRIQPLPLKKDCSEKNPDCQI----LGWGKM--ENGEFPDTIQCADVQLVSREECER 177

  Fly   192 SY-ANIKPTNICM-DTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGYPSVFTR 254
            :| ..|..:.:|. |...|..:|.||||||||....::      |:.|:|.....:|..|.|:|.
  Rat   178 AYPGKITRSMVCAGDKREGNDSCQGDSGGPLVCGGHLR------GIVSWGDMPCGSKEKPGVYTD 236

  Fly   255 ITAYLDWIGEV 265
            :..::.||..:
  Rat   237 VCTHIRWIQNI 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	65/240 (27%)
Klk6	NP_062048.1	Tryp_SPc	28..244	CDD:214473	65/240 (27%)
Klk6	NP_062048.1	Tryp_SPc	29..247	CDD:238113	67/242 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010