DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon74E and F11

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_006253206.1	Gene:	F11 / 290757	RGDID:	1309364	Length:	622	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	86/273 - (31%)
Similarity:	124/273 - (45%)	Gaps:	50/273 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 HGIGG---------------------RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDR 69
            ||.||                     |:.||..:...::|:||.|...:.:    .||.|:|.:|
  Rat   361 HGRGGISGYTLRLCKMDNVCTTKIRPRVFGGAASVHGEWPWQVTLHTTQGH----LCGGSIIGNR 421

  Fly    70 YLLTAAHC---VEKAVAITYYLGGVLRLAPRQLIRSTN----PEVHLHPDWNCQSLENDIALVRL 127
            ::||||||   .|....:..| ||::..:  ::...|.    .|:.:|..:.......||||::|
  Rat   422 WILTAAHCFSGTETPKTLRVY-GGIVNQS--EINEDTTFFRVQEMIIHDQYTSAESGFDIALLKL 483

  Fly   128 PEDALLCDSIRPIRLPGLSSSRNSYDYVPAIASGWG--RMNDESTAISDNLRYVYRFVESNEDCE 190
            .......|..|||.||  |....:..:.....:|||  :..||   :...|:.....:.|||:|:
  Rat   484 EPAMNYTDFQRPICLP--SKGDRNVVHTECWVTGWGYTKSRDE---VQSTLQKAKVPLVSNEECQ 543

  Fly   191 YSYANIKPTN--ICMD-TTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGC-TKGYPSV 251
            ..|...|.||  ||.. ..|||.||.|||||||  |........|:|:||:|:  || .|..|.|
  Rat   544 TRYRKHKITNKVICAGYKEGGKDTCKGDSGGPL--SCKHNGVWHLVGITSWGE--GCGQKERPGV 604

  Fly   252 FTRITAYLDWIGE 264
            :|.:..|:|||.|
  Rat   605 YTNVAKYVDWILE 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	79/243 (33%)
F11	XP_006253206.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..374	CDD:128519	4/12 (33%)
		Tryp_SPc	387..615	CDD:214473	79/243 (33%)
		Tryp_SPc	388..615	CDD:238113	78/242 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910