DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and Tmprss15

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_038944148.1	Gene:	Tmprss15 / 288291	RGDID:	1311046	Length:	1028	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	86/273 - (31%)
Similarity:	137/273 - (50%)	Gaps:	36/273 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LILVQGRSISCLD--MGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLT 73
            |||:|....||.:  :...:|.:|.||...:|..:|:.|.|...:.:.....|||||:|..:|::
  Rat   766 LILLQCNHKSCGEKMVTQKVGPKIVGGSDTQAGAWPWVVALYYRDRSGDRLLCGASLVSSDWLVS 830

  Fly    74 AAHCVEK----AVAITYYLGGVLR--LAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDAL 132
            |||||.:    ....|..||..::  |...|::|.....:.::|.::.:...||||::.|.....
  Rat   831 AAHCVYRRNLDPTRWTAVLGLHMQSNLTSPQVVRRVVDRIVINPHYDKRRKVNDIAMMHLEFKVN 895

  Fly   133 LCDSIRPIRLPGLSSSRNSYDYVP----AIASGWG--RMNDESTAISDNLRYVYRFVESNEDC-- 189
            ..|.|:||.||     ..:..:.|    :|| |||  ::|..||.  |.|:.....:.|||.|
  Rat   896 YTDYIQPICLP-----EENQTFTPGRMCSIA-GWGYNKINAGSTV--DVLKEADVPLVSNEKCQQ 952

  Fly   190 ---EYSYANIKPTNICMD-TTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCT-KGYP 249
               ||   :|..:.:|.. ..||..:|.|||||||:..:  .|...|:||||:|.:  |. ..:|
  Rat   953 QLPEY---DITESMLCAGYEEGGTDSCQGDSGGPLMCQE--NNRWFLVGVTSFGVQ--CALPNHP 1010

  Fly   250 SVFTRITAYLDWI 262
            .|:.|::.:::||
  Rat  1011 GVYARVSQFIEWI 1023

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	77/249 (31%)
Tmprss15	XP_038944148.1	SEA	54..155	CDD:214554
		LDLa	188..221	CDD:238060
		CUB	229..335	CDD:412131
		MAM	351..507	CDD:395504
		CUB	528..635	CDD:395345
		LDLa	647..681	CDD:238060
		Tryp_SPc	789..1025	CDD:238113	79/250 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910