Protein Alignment Jon74E and Tmprss5

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_695223.2
• Gene: Tmprss5 / 266681
• RGDID: 628625
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 263
• Identity: 76/263 - (28%)
• Similarity: 128/263 - (48%)
• Gaps: 29/263 - (11%)

  Fly    16 GR--SISCLDMG-HGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHC 77
            ||  |:.|.:.| ..:..||.||:...:.::|:|..:.:...:.    ||||:::..:::|||||
  Rat   189 GRIVSLKCSECGARPLASRIVGGQAVASGRWPWQASVMLGSRHT----CGASVLAPYWVVTAAHC 249

  Fly    78 -----VEKAVAITYYLGGVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSI 137
                 :.:..:...:.|.|...|.||...:...::..||.::.|:.:.|:||::|.......|::
  Rat   250 MYSFRLSRLSSWRVHAGLVSHSAVRQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTV 314

  Fly   138 RPIRLPGLSS--SRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVES----NEDCEYSYANI 196
            ..:.||....  .:.|..:|    ||||..:...|..||.|:.....:.|    |..|.||.| :
  Rat   315 SAVCLPAKEQHFPQGSQCWV----SGWGHTDPSHTHSSDTLQDTMVPLLSTDLCNSSCMYSGA-L 374

  Fly   197 KPTNICMDTTGGKS-TCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTK-GYPSVFTRITAYL 259
            ....:|.....|:: .|.||||||||.  |..:...|:||.|:|:  ||.: ..|.|:.::..:|
  Rat   375 THRMLCAGYLDGRADACQGDSGGPLVC--PSGDTWHLVGVVSWGR--GCAEPNRPGVYAKVAEFL 435

  Fly   260 DWI 262
            |||
  Rat   436 DWI 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	69/243 (28%)
Tmprss5	NP_695223.2	SRCR_2	106..203	CDD:464747	5/13 (38%)
		Tryp_SPc	208..441	CDD:238113	70/244 (29%)