DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and TPSG1

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_011520748.1	Gene:	TPSG1 / 25823	HGNCID:	14134	Length:	346	Species:	Homo sapiens

Alignment Length:	285	Identity:	92/285 - (32%)
Similarity:	126/285 - (44%)	Gaps:	57/285 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SCLDMGHG------IGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCV 78
            |..|:|.|      .||||.||..|.|..:|:|..|.:...:    .||.||:|.:::||||||.
Human    45 SSFDLGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVH----VCGGSLLSPQWVLTAAHCF 105

  Fly    79 EKAVAITYY---LGGV-LRLAP-----RQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLC 134
            ..::..:.|   ||.: :.|:|     ||:|..::|.       .......|||||.|.....|.
Human   106 SGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPS-------GQPGTSGDIALVELSVPVTLS 163

  Fly   135 DSIRPIRLPGLSSSRNSYDYVPAI---ASGWGRMND-ESTAISDNLRYVYRFVESNEDCEYSYAN 195
            ..|.|:.||..|.     |:.|.|   .:|||...: |......:||.|...|...|.|...|..
Human   164 SRILPVCLPEASD-----DFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPG 223

  Fly   196 -----IKPTNICMDTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTK-GYPSVFTR 254
                 ::|..:|  ..|....|..|||||||..  |..|.:..|..|:|:  ||.: ..|.|:||
Human   224 PGGSILQPDMLC--ARGPGDACQDDSGGPLVCQ--VNGAWVQAGTVSWGE--GCGRPNRPGVYTR 282

  Fly   255 ITAYLDWI--------GEVSGVHYP 271
            :.||::||        |..||  ||
Human   283 VPAYVNWIRRHITASGGSESG--YP 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	79/249 (32%)
TPSG1	XP_011520748.1	Tryp_SPc	62..290	CDD:214473	79/249 (32%)
TPSG1	XP_011520748.1	Tryp_SPc	63..293	CDD:238113	80/251 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910