Protein Alignment Jon74E and CELA3B

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: XP_047272536.1
• Gene: CELA3B / 23436
• HGNCID: 15945
• Length: 300
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 88/281 - (31%)
• Similarity: 137/281 - (48%)
• Gaps: 33/281 - (11%)

  Fly     1 MQISTILVFLLILVQGRSISCLDMGHG-----IGGRIAGGELARANQFPYQVGLSIEEPNDMYCW 60
            |.:..:...||:.|..        |:|     ...|:..||.|....:|:||.|..|:....|..
Human     1 MMLRLLSSLLLVAVAS--------GYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHT 57

  Fly    61 CGASLISDRYLLTAAHCVEKAVAITYYLG---GVLRLAPRQLIRSTNPEVHLHPDWN--CQSLEN 120
            ||.|||:..:::||.||:..:......||   ..::..|.|:|...:.::.:||.||  |.:..|
Human    58 CGGSLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGN 122

  Fly   121 DIALVRLPEDALLCDSIRPIRLPGLSSSRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVES 185
            ||||::|...|.|.|:::...||.......  :..|...:||||:.... .:.|.|:.....|..
Human   123 DIALIKLSRSAQLGDAVQLASLPPAGDILP--NETPCYITGWGRLYTNG-PLPDKLQEALLPVVD 184

  Fly   186 NEDC---EYSYANIKPTNICMDTTGG--KSTCTGDSGGPLVYSDPVQNADILI-GVTSYGKKSGC 244
            .|.|   .:..:::|.|.:|   .||  :|.|.|||||||  :.|.::....: ||||:....||
Human   185 YEHCSRWNWWGSSVKKTMVC---AGGDIRSGCNGDSGGPL--NCPTEDGGWQVHGVTSFVSAFGC 244

  Fly   245 -TKGYPSVFTRITAYLDWIGE 264
             |:..|:||||::|::|||.|
Human   245 NTRRKPTVFTRVSAFIDWIEE 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	79/242 (33%)
CELA3B	XP_047272536.1	Tryp_SPc	29..265	CDD:238113	80/243 (33%)