DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	245	Identity:	78/245 - (31%)
Similarity:	129/245 - (52%)	Gaps:	19/245 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITYYLG--GVLR 93
            ||.||..|....:|:||.|.:   |::: .||.:|||:.::||||||.:......|:..  ||..
Mouse   185 RIIGGMQAEPGDWPWQVSLQL---NNVH-HCGGALISNMWVLTAAHCFKSYPNPQYWTATFGVST 245

  Fly    94 LAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPGLSSSRNSYDYVPAI 158
            ::||..:|..  .:..|..::..:.:||||:|:|........:|..:.||  ::::|......|.
Mouse   246 MSPRLRVRVR--AILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLP--AATQNIIPGSVAY 306

  Fly   159 ASGWGRMNDESTAISDNLRYVYRFVESNEDCE----YSYANIKPTNICMD-TTGGKSTCTGDSGG 218
            .:|||.:.....|:: |||.....:.|:|:|.    || .::.|..:|.. .:|....|.|||||
Mouse   307 VTGWGSLTYGGNAVT-NLRQGEVRIISSEECNTPAGYS-GSVLPGMLCAGMRSGAVDACQGDSGG 369

  Fly   219 PLVYSDPVQNADILIGVTSYGKKSGCTKGYPSVFTRITAYLDWIGEVSGV 268
            |||..|. :....::|:.|:|.:.| ....|.|:||:|||.:||.:.:|:
Mouse   370 PLVQEDS-RRLWFVVGIVSWGYQCG-LPNKPGVYTRVTAYRNWIRQQTGI 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	75/237 (32%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699
		Tryp_SPc	185..411	CDD:214473	75/237 (32%)
		Tryp_SPc	186..414	CDD:238113	76/239 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910