Protein Alignment Jon74E and F11

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 85/275 - (30%)
• Similarity: 130/275 - (47%)
• Gaps: 51/275 - (18%)

  Fly    26 HGIGG---------------------RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDR 69
            ||.||                     ||.||..:...::|:||.|....|...:. ||.|:|.::
Human   362 HGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHL-CGGSIIGNQ 425

  Fly    70 YLLTAAHC---VEKAVAITYYLGGVLRLAPRQLIRSTN----PEVHLHPDWNCQSLENDIALVRL 127
            ::||||||   ||....:..| .|:|..:  ::...|:    .|:.:|..:.......||||::|
Human   426 WILTAAHCFYGVESPKILRVY-SGILNQS--EIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKL 487

  Fly   128 PEDALLCDSIRPIRLPGLSSSRNSYDYVPAIASGWG--RMNDESTAISDNLRYVYRFVESNEDCE 190
            .......||.|||.||  |....:..|.....:|||  ::.|:   |.:.|:.....:.:||:|:
Human   488 ETTVNYTDSQRPICLP--SKGDRNVIYTDCWVTGWGYRKLRDK---IQNTLQKAKIPLVTNEECQ 547

  Fly   191 YSYANIKPTN--ICMD-TTGGKSTCTGDSGGPLVYSDPVQNADI--LIGVTSYGKKSGCT-KGYP 249
            ..|...|.|:  ||.. ..|||..|.|||||||    ..::.::  |:|:||:|:  ||. :..|
Human   548 KRYRGHKITHKMICAGYREGGKDACKGDSGGPL----SCKHNEVWHLVGITSWGE--GCAQRERP 606

  Fly   250 SVFTRITAYLDWIGE 264
            .|:|.:..|:|||.|
Human   607 GVYTNVVEYVDWILE 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	78/245 (32%)
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	4/12 (33%)
		Tryp_SPc	389..619	CDD:238113	77/244 (32%)