DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and St14

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_036010597.1	Gene:	St14 / 19143	MGIID:	1338881	Length:	875	Species:	Mus musculus

Alignment Length:	264	Identity:	78/264 - (29%)
Similarity:	117/264 - (44%)	Gaps:	48/264 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITY--------Y 87
            |:.||..|...::|:||.|.......:   |||||||..:|::||||.:......|        :
Mouse   634 RVVGGTNADEGEWPWQVSLHALGQGHL---CGASLISPDWLVSAAHCFQDDKNFKYSDYTMWTAF 695

  Fly    88 LG----------GVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRL 142
            ||          ||..|..:::|        .||.:|..:.:.||||:.|.:.......:|||.|
Mouse   696 LGLLDQSKRSASGVQELKLKRII--------THPSFNDFTFDYDIALLELEKSVEYSTVVRPICL 752

  Fly   143 PGLSSSRNSYDYVPAI-ASGWGRMNDESTAI----SDNLRYVYRFVESNEDCE-YSYANIKPTNI 201
            |   .:.:.:....|| .:|||...:..|..    ...:|.:     :...|| .....|.|..:
Mouse   753 P---DATHVFPAGKAIWVTGWGHTKEGGTGALILQKGEIRVI-----NQTTCEDLMPQQITPRMM 809

  Fly   202 CMD-TTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCT-KGYPSVFTRITAYLDWIGE 264
            |:. .:||..:|.|||||||..::. .......||.|:|:  ||. :..|.|:||:....|||.|
Mouse   810 CVGFLSGGVDSCQGDSGGPLSSAEK-DGRMFQAGVVSWGE--GCAQRNKPGVYTRLPVVRDWIKE 871

  Fly   265 VSGV 268
            .:||
Mouse   872 HTGV 875

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	73/256 (29%)
St14	XP_036010597.1	SEA	108..198	CDD:396113
		CUB	247..352	CDD:238001
		CUB	360..464	CDD:238001
		LDLa	474..506	CDD:238060
		LDLa	512..543	CDD:238060
		LDLa	545..579	CDD:238060
		LDLa	587..622	CDD:238060
		Tryp_SPc	635..872	CDD:238113	74/258 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920