DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and Klk1b4

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_035045.2	Gene:	Klk1b4 / 18048	MGIID:	97320	Length:	256	Species:	Mus musculus

Alignment Length:	223	Identity:	70/223 - (31%)
Similarity:	101/223 - (45%)	Gaps:	36/223 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 CGASLISDRYLLTAAHCVEKAVAITYYLGGVLRLAP---RQLIRSTNPEVHLHPDWNCQSL---- 118
            ||..|:...::||||||......:.......|...|   .:|:....|    |||:|...|
Mouse    45 CGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIP----HPDFNMSLLNEHT 105

  Fly   119 -------ENDIALVRLPEDALLCDSIRPIRLPGLSSSRNSYDYVPAIASGWGRMNDESTAISDNL 176
                   .||:.|:||.:.|.:.|.::||.||.......|    ..:|||||..........|:|
Mouse   106 PQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGS----TCLASGWGSTTPIKFKYPDDL 166

  Fly   177 RYVYRFVESNEDCEYSYANIKPTN--IC---MDTTGGKSTCTGDSGGPLVYSDPVQNADILIGVT 236
            :.|...:..||||:.:: .:|.|:  :|   ||  ||..||..||||||:..      .||.|:|
Mouse   167 QCVNLKLLPNEDCDKAH-EMKVTDAMLCAGEMD--GGSYTCEHDSGGPLICD------GILQGIT 222

  Fly   237 SYGKKSGCTKGYPSVFTRITAYLDWIGE 264
            |:|.:.......|||:|::..:..||.|
Mouse   223 SWGPEPCGEPTEPSVYTKLIKFSSWIRE 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	67/219 (31%)
Klk1b4	NP_035045.2	Tryp_SPc	13..251	CDD:238113	70/223 (31%)
Klk1b4	NP_035045.2	Activation peptide homolog	18..24
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010