Protein Alignment Jon74E and CTRB1

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001897.4
• Gene: CTRB1 / 1504
• HGNCID: 2521
• Length: 263
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 77/276 - (27%)
• Similarity: 127/276 - (46%)
• Gaps: 52/276 - (18%)

  Fly    19 ISCLDM-----GHGIG---------GRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDR 69
            :||..:     |.|:.         .||..||.|....:|:||.|   :....:.:||.||||:.
Human     7 LSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSL---QDKTGFHFCGGSLISED 68

  Fly    70 YLLTAAHC----VEKAVAITYYLGG------VLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIAL 124
            :::|||||    .:..||..:..|.      ||::|          :|..:|.::..::.|||.|
Human    69 WVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIA----------KVFKNPKFSILTVNNDITL 123

  Fly   125 VRLPEDALLCDSIRPIRLPGLSSSRNSYDYVPA----IASGWGRMNDESTAISDNLRYVYRFVES 185
            ::|...|....::..:.||      ::.|..||    ..:|||:....:....|.|:.....:.|
Human   124 LKLATPARFSQTVSAVCLP------SADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLS 182

  Fly   186 NEDCEYSYA-NIKPTNICMDTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGYP 249
            |.:|:.|:. .|....||...: |.|:|.||||||||...  ..|..|:|:.|:|..: |:...|
Human   183 NAECKKSWGRRITDVMICAGAS-GVSSCMGDSGGPLVCQK--DGAWTLVGIVSWGSDT-CSTSSP 243

  Fly   250 SVFTRITAYLDWIGEV 265
            .|:.|:|..:.|:.::
Human   244 GVYARVTKLIPWVQKI 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	72/245 (29%)
CTRB1	NP_001897.4	Tryp_SPc	34..259	CDD:238113	72/247 (29%)