DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and CLIPD3

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_321698.4	Gene:	CLIPD3 / 1281744	VectorBaseID:	AGAP001433	Length:	670	Species:	Anopheles gambiae

Alignment Length:	261	Identity:	86/261 - (32%)
Similarity:	115/261 - (44%)	Gaps:	43/261 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCV----EKAVAITYYLGG 90
            |||.||..|...|:|:...:.:........|||.|||..:|:||||||.    ::..|...:
Mosquito   423 GRIVGGIEAPTGQWPWMAAIFLHGTKRTEFWCGGSLIGTKYILTAAHCTRDSRQRPFAARQF--- 484

  Fly    91 VLRLAPRQLIRSTNP---------EVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPG-- 144
            .:||....|.....|         ||..||.::.....|||||:.|.:.......:.|:.|||
Mosquito   485 TVRLGDIDLSTDGEPSAPVTYKVTEVRAHPRFSRVGFYNDIALLVLDKPVRKSKYVIPVCLPGPN 549

  Fly   145 ------LSSSRNSYDYVPAIASGWGRM---NDESTAISDNLRYVYRFVESNEDCEYSYAN-IKPT 199
                  |:..|       |...|||..   ..|||........|:|    ||||..:|.. |...
Mosquito   550 LPSKERLAGRR-------ATVVGWGTTYYGGKESTKQQQATLPVWR----NEDCNRAYFQPITDN 603

  Fly   200 NICMD-TTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGYPSVFTRITAYLDWIG 263
            .:|.. :.||...|.|||||||:..  |:.....:||.|:|.|.| ..|||.|:|||:.|::||.
Mosquito   604 FVCAGFSEGGVDACQGDSGGPLMML--VEARWTQVGVVSFGNKCG-EPGYPGVYTRISEYMEWIR 665

  Fly   264 E 264
            |
Mosquito   666 E 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	82/256 (32%)
CLIPD3	XP_321698.4	CLIP	292..335	CDD:197829
		Tryp_SPc	424..664	CDD:214473	82/256 (32%)
		Tryp_SPc	425..667	CDD:238113	84/259 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910