DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and AgaP_AGAP001707

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_321381.5	Gene:	AgaP_AGAP001707 / 1281466	VectorBaseID:	AGAP001707	Length:	511	Species:	Anopheles gambiae

Alignment Length:	252	Identity:	56/252 - (22%)
Similarity:	95/252 - (37%)	Gaps:	45/252 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 IEEPNDMYCW----------------CGASLISDRYLLTAAHCVEKAVA-------ITYYLG--G 90
            |..|...:.|                ||:::|.:|:|:|||||:..::.       :|...|  .
Mosquito   264 IRSPKGQFPWAAPIFDTGVPAKPKYICGSTIIGERHLVTAAHCMYDSIGNPRSANDLTTVPGMHN 328

  Fly    91 VLRLAPRQLIRSTNPEVHLHPDWNCQS---LENDIALVRLPEDALLCDSIRPIRLPGLSSSRNSY 152
            :.......|...:..::.:|.|:..:.   |:.|||::.:.:.....:.:|||.|...|.:....
Mosquito   329 IDNFFDADLQERSVKKIFIHEDYYFEDSILLDTDIAVMLIDQPLTYNNLVRPICLWQESDNLEQI 393

  Fly   153 DYVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSYANIKPTN---ICMDTTGGKSTCTG 214
            .......||||...|.:.....   ||...|.....|..:...:...|   .|.| ..|...|||
Mosquito   394 VGQKGFVSGWGVTEDGNAKYPS---YVTATVVDRRTCTRNLERLIAGNARIFCAD-GHGSVPCTG 454

  Fly   215 DSGGPLVYSDPVQNAD--ILIGVTSYGKKS----GCTKGYPSVFTRITAYLDWIGEV 265
            |||..||    ::...  .:.|:.|.|:..    .|.:....::|.|..:..|:..|
Mosquito   455 DSGSGLV----IKRGSRYYIRGIVSVGQYDPNTLTCARDKYVLYTDIAPFRYWLSRV 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	54/247 (22%)
AgaP_AGAP001707	XP_321381.5	GD_N	50..150	CDD:292649
		Tryp_SPc	261..507	CDD:238113	55/250 (22%)
		Tryp_SPc	261..503	CDD:214473	54/246 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910