DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and AgaP_AGAP001798

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_321263.5	Gene:	AgaP_AGAP001798 / 1281317	VectorBaseID:	AGAP001798	Length:	664	Species:	Anopheles gambiae

Alignment Length:	291	Identity:	70/291 - (24%)
Similarity:	106/291 - (36%)	Gaps:	67/291 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 IAGGELARANQFPYQVGL----------SIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITY 86
            |.||......:.|:.:.:          .:..|:..|. ||.|::::|.::|||||......  :
Mosquito   388 IIGGRNVSIAEVPWHMAIYKNLHDDTLDDLRSPDWQYV-CGGSILTERLVVTAAHCFWATEG--F 449

  Fly    87 YLGGVLRLA--------------PRQLIRSTNPEVHLH-----PDWNCQS--LENDIALVRLPED 130
            :.....|||              |.|..       |:|     |.:...|  ...|||:|.|...
Mosquito   450 FDKRFFRLAAGKYRRDIAAIEALPAQYF-------HIHEILTQPQYQDFSGYYNLDIAIVVLNGF 507

  Fly   131 ALLCDSIRPIRLPGLSSSRNSYDYVPAI---ASGWGRMNDESTAISDNLRYVYRFVE-SNED--- 188
            ......||||.|.....:.:.....||.   .:|||     .|..:.||..|.:.:: :..|
Mosquito   508 ISFRTYIRPICLERNLRTESEKRIRPASVGRVAGWG-----FTTSTGNLSSVLKVIDIATVDYVT 567

  Fly   189 C-EYSYANIKP----TNICMDT-TGGKSTCTGDSGG--PLVYSDPVQNADI--LIGVTSYGKKS- 242
            | |:|....:|    ...|..: ..|.|.|.|||||  .|...:|.....:  |.|:.|...::
Mosquito   568 CREFSPVAYRPFLTGDKFCAGSPRTGTSVCQGDSGGGFALGKEEPGGGDTVYYLYGLVSSAPRAA 632

  Fly   243 --GCTKGYPSVFTRITAYLDWIGEVSGVHYP 271
              ||.......||.:..|:..|.:... .||
Mosquito   633 DGGCDNNKYVAFTEVQNYIPMILDAES-RYP 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	67/280 (24%)
AgaP_AGAP001798	XP_321263.5	LDLa	31..62	CDD:238060
		LDLa	71..103	CDD:197566
		LDLa	121..152	CDD:197566
		LDLa	162..194	CDD:238060
		CCP	239..304	CDD:153056
		Tryp_SPc	388..654	CDD:214473	67/280 (24%)
		Tryp_SPc	388..654	CDD:238113	67/280 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910