DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and AgaP_AGAP011908

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_320621.4	Gene:	AgaP_AGAP011908 / 1280755	VectorBaseID:	AGAP011908	Length:	391	Species:	Anopheles gambiae

Alignment Length:	271	Identity:	85/271 - (31%)
Similarity:	122/271 - (45%)	Gaps:	48/271 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ILVQGRSISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAH 76
            ::||.:...|   |.....:|.||.:|..|::...|||.  :|..:..:|..::||.||:|||||
Mosquito   137 LVVQPQECDC---GWSRTAKIVGGSVAGVNEYTAMVGLL--DPLTVNVFCSGAIISSRYVLTAAH 196

  Fly    77 C---------VEKAVAITYYLGGVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDAL 132
            |         |:..|....|..|:  ..|...|.:.. ::..|..:|.|:..|||||::...:..
Mosquito   197 CARTIPSVSRVQALVGDHDYRSGL--DTPYSAIYNIE-QIISHEYYNEQTRNNDIALLKTSTEMD 258

  Fly   133 LCDSIRPIRLPGLSSSRNSYDYVPAIASGWGRMNDESTA----ISDNLRYVYRFVESNEDCEYSY 193
            ....:.||.|| .:.|..|:..:....:|||     :|:    :|..||.....|..|.:|...|
Mosquito   259 FNRGVGPICLP-FTYSTYSFGGLSVDIAGWG-----TTSFGGPMSTILRKTTLNVLQNANCTAPY 317

  Fly   194 ANIKPTNICMDTTGGKSTCTGDSGGPL-------VYSDPVQNADILIGVTSYGKKSGCTKGYPSV 251
            .|  ...||.... |:.:|..||||.|       :||         ||:.|||  |.|....|||
Mosquito   318 VN--DQKICTFAV-GRDSCQYDSGGALFLRGSQRMYS---------IGIISYG--SACAASTPSV 368

  Fly   252 FTRITAYLDWI 262
            .||:||||.||
Mosquito   369 ATRVTAYLSWI 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	79/250 (32%)
AgaP_AGAP011908	XP_320621.4	CUB	26..>106	CDD:294042
		Tryp_SPc	153..379	CDD:214473	79/250 (32%)
		Tryp_SPc	154..382	CDD:238113	81/251 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910