DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and CLIPB1

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_307756.2	Gene:	CLIPB1 / 1269160	VectorBaseID:	AGAP003251	Length:	372	Species:	Anopheles gambiae

Alignment Length:	265	Identity:	88/265 - (33%)
Similarity:	134/265 - (50%)	Gaps:	44/265 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCW-CGASLISDRYLLTAAHCVEKAVAITYYLGGVLRL 94
            ||.||.::..:.:|:...:...:.::.|.: ||..||.::|:||||||:| .|..|:.:..| ||
Mosquito   114 RIVGGGVSPIDGYPWLTRIQYYKGSNRYGFHCGGVLIHNQYVLTAAHCIE-GVPSTWIVYQV-RL 176

  Fly    95 AP------------------RQLIRSTNPEVHLHPDWNCQSLE--NDIALVRLPEDALLCDSIRP 139
            ..                  |.::  .|..| :|||:..|:..  |||||::|.|.....|.|||
Mosquito   177 GEFDTTTTIDCVEDDCADPVRDVL--INAYV-VHPDYYKQNGADYNDIALLQLSETVEFTDFIRP 238

  Fly   140 IRLPGLSSSR-----NSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSYANIK-- 197
            |.||....||     ..|    |..:|||: .:.||:.:..|......|: ||.|..::::|:
Mosquito   239 ICLPTSEESRTVNLTGKY----ATVAGWGQ-TENSTSSTKKLHLRVPVVD-NEVCADAFSSIRLE 297

  Fly   198 --PTNICMDTTGGKSTCTGDSGGPLV-YSDPVQNAD--ILIGVTSYGKKSGCTKGYPSVFTRITA 257
              ||.:|.....||.:|.|||||||: |.|...:..  .|||:.|:|.:...|.|.|.|:||::.
Mosquito   298 IIPTQLCAGGEKGKDSCRGDSGGPLMRYGDGRSSTKSWYLIGLVSFGLEQCGTDGVPGVYTRMSE 362

  Fly   258 YLDWI 262
            |:||:
Mosquito   363 YMDWV 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	87/263 (33%)
CLIPB1	XP_307756.2	CLIP	32..85	CDD:288855
		Tryp_SPc	114..367	CDD:214473	87/263 (33%)
		Tryp_SPc	115..367	CDD:238113	86/262 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910