Protein Alignment Jon74E and PRSS21

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 84/290 - (28%)
• Similarity: 121/290 - (41%)
• Gaps: 80/290 - (27%)

  Fly    28 IGGRIAGGELARANQFPYQVGLSIEEPNDMYCW----CGASLISDRYLLTAAHCVE--------- 79
            |..||.|||.|...::|:|..|.:        |    ||.||:|.|:.||||||.|
Human    38 ITSRIVGGEDAELGRWPWQGSLRL--------WDSHVCGVSLLSHRWALTAAHCFETYSDLSDPS 94

  Fly    80 ------------------KAVAITYYLGGVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVR 126
                              :|....|::..:. |:||.|..|                ..|||||:
Human    95 GWMVQFGQLTSMPSFWSLQAYYTRYFVSNIY-LSPRYLGNS----------------PYDIALVK 142

  Fly   127 LPEDALLCDSIRPIRLPGLSSSRNSYDYVPAIASGWGRM-NDESTAISDNLRYVYRFVESNEDC- 189
            |.........|:||.|.  :|:....:......:|||.: .||:......|:.|...:.:|..|
Human   143 LSAPVTYTKHIQPICLQ--ASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCN 205

  Fly   190 ----EYSY-ANIKPTNICM-DTTGGKSTCTGDSGGPLVYSDPVQNADIL---IGVTSYGKKSGCT 245
                :||: .:|....:|. :..|||..|.|||||||..     |.:.|   |||.|:|  .||.
Human   206 HLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC-----NKNGLWYQIGVVSWG--VGCG 263

  Fly   246 K-GYPSVFTRITAYLDWIGEV---SGVHYP 271
            : ..|.|:|.|:.:.:||.::   ||:..|
Human   264 RPNRPGVYTNISHHFEWIQKLMAQSGMSQP 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	78/273 (29%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	79/274 (29%)