DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and tmprss9

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_002940084.3	Gene:	tmprss9 / 100489279	XenbaseID:	XB-GENE-993973	Length:	1151	Species:	Xenopus tropicalis

Alignment Length:	250	Identity:	85/250 - (34%)
Similarity:	125/250 - (50%)	Gaps:	36/250 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVE--------KAVAITYY 87
            :|.||..:...::|:||.|.:......   |||.|||||:||:||||.:        .|...|.:
Frog   918 KIVGGSGSVRGEWPWQVSLWLRRKEHK---CGAVLISDRWLLSAAHCFDIYSDPKLWAAYLGTPF 979

  Fly    88 LGGVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPGLS-----S 147
            |.|| .....::.|     :|.||.:|..:|:||:||:.||......:.||||.||.:|     .
Frog   980 LNGV-EGRVEKIFR-----IHKHPFYNVYTLDNDVALLELPSPLTYTNLIRPICLPDISHIFPEG 1038

  Fly   148 SRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSY-ANIKPTNICMD-TTGGKS 210
            :|       ...:||| ...|..|:|..|:.....:..::.|:..| ..|.|..:|.. ..||..
Frog  1039 TR-------CFITGWG-STKEGGAMSRQLQKASVSIVGDQTCKKFYPIQISPRMLCAGFMQGGVD 1095

  Fly   211 TCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGY-PSVFTRITAYLDWIGE 264
            :|:||:||||...:| .....|.|:||:|  .||.:.| |.|:||||:..:|||:
Frog  1096 SCSGDAGGPLACREP-SGRWFLAGITSWG--YGCARPYFPGVYTRITSVRNWIGQ 1147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	82/246 (33%)
tmprss9	XP_002940084.3	SEA	60..156	CDD:396113
		LDLa	186..221	CDD:238060
		Tryp_SPc	234..463	CDD:214473
		Tryp_SPc	547..774	CDD:238113
		LDLa	871..906	CDD:238060
		Tryp_SPc	919..1145	CDD:238113	82/245 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920