Protein Alignment Nedd4 and Wwtr1

DIOPT Version :9

• Sequence 1: NP_648993.1
• Gene: Nedd4 / 39958
• FlyBaseID: FBgn0259174
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: NP_001161753.1
• Gene: Wwtr1 / 97064
• MGIID: 1917649
• Length: 452
• Species: Mus musculus
• Alignment Length: 432
• Identity: 87/432 - (20%)
• Similarity: 136/432 - (31%)
• Gaps: 172/432 - (39%)

  Fly   202 AFIRE------TREQSEPSSGNSDGE-----WEHVEA----------TNAGETS--AQPH----- 238
            :|.:|      :|:.|..|||...|.     .:||.:          |.||...  ||.|
Mouse   108 SFFKEPDSGSHSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLGTGAGAAGGPAQQHAHLRQ 172

  Fly   239 -PFPTGGHDALPAGWEERQDANGRTYYVNHTARTTQWDRP-TVLN---SHSSQSTDDQLASDFQR 298
             .:.......||.|||....|.|:.|::||..:.|.|..| .|:|   :|.:
Mouse   173 QSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKVMNQPLNHVN------------- 224

  Fly   299 RFHISVDDTESGRSADSISHNSIEDNNNAAGLAYTPKTAATSSAPPNTPTNNNGILAQIAMQYRA 363
             .|.|:..|...:.:.::|..::..|:.      ..:..|||.:|.|.||.|
Mouse   225 -LHPSITSTSVPQRSMAVSQPNLAMNHQ------HQQVVATSLSPQNHPTQN------------- 269

  Fly   364 EEDQDPTVDHTSFVYNSLRHPVAHRQPEISATSLQNDLRPVREAPGVPDIAITNPFTRRAAGNMA 428
                                     ||    |.|.:          ||:...|.
Mouse   270 -------------------------QP----TGLMS----------VPNALTTQ----------- 284

  Fly   429 GGAGWQQERRRQQMQLHIQQHQQRQQQQQQNRILLDVDHRQQEPQHRGQRHQQQHRPSNEDTDHT 493
                 ||::::.::| .||..::|.:.:|:..:..:....:|.|.                  .|
Mouse   285 -----QQQQQKLRLQ-RIQMERERIRMRQEELMRQEAALCRQLPM------------------ET 325

  Fly   494 DSHNPSDISAPSTRRNSEEDNAAVP--------PMEQNT------GGEEEPLPPRWSMQVAPNGR 544
            ::..|.:..|.||...|..::::.|        ..||:|      |....|..|.
Mouse   326 ETMAPVNTPAMSTDMRSVTNSSSDPFLNGGPYHSREQSTDSGLGLGCYSVPTTPE---------- 380

  Fly   545 TFFIDHASRRTTWIDPRNGRASPM---PNQTRRVEDDLGPLP 583
                |..|.........|...:||   |.|| |..|.|..||
Mouse   381 ----DFLSNMDEMDTGENSGQTPMTVNPQQT-RFPDFLDCLP 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nedd4	NP_648993.1	C2_NEDD4_NEDD4L	71..204	CDD:175999	0/1 (0%)
		WW	248..277	CDD:278809	12/28 (43%)
		WW	531..560	CDD:278809	3/28 (11%)
		WW	581..613	CDD:197736	2/3 (67%)
		HECTc	650..1003	CDD:238033
		HECTc	674..1003	CDD:214523
Wwtr1	NP_001161753.1	WW	182..213	CDD:197736	12/30 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810