DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nedd4 and yki

DIOPT Version :9

Sequence 1:NP_648993.1 Gene:Nedd4 / 39958 FlyBaseID:FBgn0259174 Length:1007 Species:Drosophila melanogaster
Sequence 2:NP_001350857.1 Gene:yki / 37851 FlyBaseID:FBgn0034970 Length:418 Species:Drosophila melanogaster


Alignment Length:362 Identity:77/362 - (21%)
Similarity:135/362 - (37%) Gaps:105/362 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   339 TSSAPPNT---------------PTNNNGILAQIAMQYRAEEDQDPTVDHTSFVYNSLRHPVAHR 388
            |.||..||               |..:|.::.::        :|| |.|:...:::|:.:|...:
  Fly    27 TMSASSNTNSLIEKEIDDEDMLSPIKSNNLVVRV--------NQD-TDDNLQALFDSVLNPGDAK 82

  Fly   389 QPEISATSLQNDLRPVREAPGVPDIAITNPFTRRAAGNMAGG---AGWQQERRRQQMQLHIQQ-- 448
            :|      ||..|| :|:   :|:...|.|....:..|.|..   ||.|...........:||  
  Fly    83 RP------LQLPLR-MRK---LPNSFFTPPAPSHSRANSADSTYDAGSQSSINIGNKASIVQQPD 137

  Fly   449 ---------HQQRQQQQQQNRILLDVDHRQQEPQHRGQRHQQQHRPSNEDTDHTDSHNPSDISAP 504
                     ..|.|...|.:|:.:.....:..|....|.:..:.| |:....:..:.|||....|
  Fly   138 GQSPIAAIPQLQIQPSPQHSRLAIHHSRARSSPASLQQNYNVRAR-SDAAAANNPNANPSSQQQP 201

  Fly   505 S----TRRNSEEDNAAVP------------------PMEQNTGGEEE----------------PL 531
            :    ...:::|..:..|                  ||...|..:::                .|
  Fly   202 AGPTFPENSAQEFPSGAPASSAIDLDAMNTCMSQDIPMSMQTVHKKQRSYDVISPIQLNRQLGAL 266

  Fly   532 PPRWSMQVAPNGRTFFIDHASRRTTWIDPR------------------NGRASPMPNQTRRVEDD 578
            ||.|......:|:.::::|.::.|.|.|||                  :...:.....|..:.::
  Fly   267 PPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVLQTTKQTTTSTIANN 331

  Fly   579 LGPLPEGWEERVHTDGRVFYIDHNTRTTQWEDPRLSN 615
            |||||:|||:.|...|.:::|:|..|||.|.|||:.:
  Fly   332 LGPLPDGWEQAVTESGDLYFINHIDRTTSWNDPRMQS 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nedd4NP_648993.1 C2_NEDD4_NEDD4L 71..204 CDD:175999
WW 248..277 CDD:278809
WW 531..560 CDD:278809 8/28 (29%)
WW 581..613 CDD:197736 16/31 (52%)
HECTc 650..1003 CDD:238033
HECTc 674..1003 CDD:214523
ykiNP_001350857.1 HUL4 <261..>404 CDD:227354 31/108 (29%)
WW 266..295 CDD:395320 8/28 (29%)
WW 335..364 CDD:395320 13/28 (46%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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