| Sequence 1: | NP_648993.1 | Gene: | Nedd4 / 39958 | FlyBaseID: | FBgn0259174 | Length: | 1007 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_006240148.1 | Gene: | Hectd1 / 362736 | RGDID: | 1561653 | Length: | 2610 | Species: | Rattus norvegicus |
| Alignment Length: | 1277 | Identity: | 247/1277 - (19%) |
|---|---|---|---|
| Similarity: | 402/1277 - (31%) | Gaps: | 480/1277 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 6 SGLVAAAALPVPSSSSSVAGGDVPRPPPR---------RRAASVAGQQQTR-------------- 47
Fly 48 -----------------QEFGNGYTP------RRSLAAVNDSGDSCHLRIVVLTGQSLAKKDIFG 89
Fly 90 ASDPYVRIDLNTINGDINIDSVLTKTKKKTLNPTWNE------EFIFRVKPSEHKLVFQVFDENR 148
Fly 149 LTRDDFLGMVELTLVNLPTEQEGRTIGEQSYTLRP--RRSVGAKSRIKGTLRIYHAFIRETREQS 211
Fly 212 EPSSGNSDGEWEHVEATNAGETSAQPHPFPTGGHDALPAGWEERQDANGRTYYVNHTARTTQWDR 276
Fly 277 PTVLNSHSS----------------QSTDDQLASDFQRRFHI--SVDDTESGRSADSISHNSIED 323
Fly 324 --------NNNAAGLAYTPKTAATSSAPPNTPTNNNGILAQI-----AMQYRAEEDQDPTVDHTS 375
Fly 376 FVYNSLRHPVAH-RQPEISATSLQNDLRPVREAPGVPDIAITNPFTRRAAGNMAGGAGWQQERRR 439
Fly 440 QQMQL-----HIQQHQQRQQQQQ------QNRILLDVDHRQQEPQHRGQRHQQQHRPSNEDTDHT 493
Fly 494 DSHNPSDI--------------SAPSTRRNSEEDNAAVP----PMEQNTGGE---------EEPL 531
Fly 532 P------PRWSMQVAPNGRTFFIDH-------------ASRRTTWIDPRNGRASPMPNQTRRVED 577
Fly 578 DLGPLPEGWEERVHTDGRVFYIDHNTRTTQWEDP------RLSNPNIAGQAVPYSRDYKQKYEYF 636
Fly 637 KSHIRKPTNVPNKFEIRIRRTSILEDSYRIISSVTKTDLLKTKLWVEFEGE--TGLDYGGLAREW 699
Fly 700 FYLLSKEMFNPYYG--LFEYSAMDNYTLQINNGSGL----------CN-------------EEHL 739
Fly 740 SYFKFIGRIAGMAVYHGKLLDAFFIRPFYKMMLQKPI---------------DLKDMES---VDT 786
Fly 787 E------------------------------YYNSLM-W---------------------IK--- 796
Fly 797 ----------ENDPRILELT---------------------FCLDEDVFGQKSQHELKPGGANID 830
Fly 831 VTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHELELLMCGIQN-----I 890
Fly 891 DVKDWRENTLYKGDYHMNHIIIQWFWRAVLSFSNEMRSRLLQFVTGTSRVPMNGFKELYGSNGPQ 955
Fly 956 MFTIEKW-GTPNNFPRAHTCFNRLDLPPYEGYLQLKDKLIKA 996 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nedd4 | NP_648993.1 | C2_NEDD4_NEDD4L | 71..204 | CDD:175999 | 28/140 (20%) |
| WW | 248..277 | CDD:278809 | 7/28 (25%) | ||
| WW | 531..560 | CDD:278809 | 10/47 (21%) | ||
| WW | 581..613 | CDD:197736 | 7/37 (19%) | ||
| HECTc | 650..1003 | CDD:238033 | 101/484 (21%) | ||
| HECTc | 674..1003 | CDD:214523 | 96/460 (21%) | ||
| Hectd1 | XP_006240148.1 | Ank_2 | 366..457 | CDD:289560 | |
| ANK repeat | 366..393 | CDD:293786 | |||
| ANK | 369..479 | CDD:238125 | |||
| ANK repeat | 396..426 | CDD:293786 | |||
| ANK repeat | 428..457 | CDD:293786 | |||
| F5_F8_type_C | 1107..1240 | CDD:304887 | |||
| MIB_HERC2 | 1277..1335 | CDD:284184 | |||
| HECTc | 2131..2608 | CDD:238033 | 105/518 (20%) | ||
| HECTc | 2155..2607 | CDD:214523 | 100/478 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5021 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.900 | |||||