Protein Alignment Edc3 and Edc3

DIOPT Version :9

• Sequence 1: NP_648992.1
• Gene: Edc3 / 39957
• FlyBaseID: FBgn0036735
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_036010982.1
• Gene: Edc3 / 353190
• MGIID: 2142951
• Length: 517
• Species: Mus musculus
• Alignment Length: 673
• Identity: 182/673 - (27%)
• Similarity: 281/673 - (41%)
• Gaps: 208/673 - (30%)

  Fly     7 DWIGCAVSIACDEVLGVFQGLIKQIS--AEEITIVRAFRNG----VPLRKQNAEVVLKCTDIRSI 65
            ||:|..|||.|.:.|||:||.:..:.  ::.|::.|.|.||    ||      ||..:..||..:
Mouse     4 DWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVP------EVTFRAGDITEL 62

  Fly    66 DLIEPAKQDLDGHTAPPPVVNKPTPVKLPHFSNILGKQQQLQLQQQQQQLQLQQQQKQQFQEQER 130
            .::|          .|.|                 |..||:
Mouse    63 KILE----------IPGP-----------------GDNQQV------------------------ 76

  Fly   131 EQDLPSTPRSRANDNGRVAAGGASSSSGPRG-NFNSALSDKMHQLKLIETNGSNGTLRTPQTSRA 194
             .||..|                  ..||.| .:..::|.          ||:...::.|.:|
Mouse    77 -GDLHQT------------------ELGPSGVGYQMSISQ----------NGTGKVVKKPASS-- 110

  Fly   195 SSAQQQPQISTTPNSVAAFFGNMIPPKVEVKLGSYVSNTRESYCSSSGDSGEATGLSLGSSKPID 259
                     |:.|.|        ||.:.:||......:.::..||.|........||...|
Mouse   111 ---------SSAPQS--------IPKRTDVKSQDVAISPQQQQCSKSYVDRHMESLSQSKS---- 154

  Fly   260 IVSNGDGFYKQTAASSYGNTNGNVRRNGNANNNGNGTGNGSYTNGNG--NGNGKNKRNRVRRESS 322
                                   .||..|:.::.:...|.:....:|  ||..|||.:.
Mouse   155 -----------------------FRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDE------ 190

  Fly   323 MRQQQVQLTFGSEADDPLIHEDFDFEGNLALFDKQAIWDDIESTTQKPDVVRHIVNNHHHKPEQK 387
                    .||.:.:: |...|||||||||||||.|::::|::..::.......|.|  .:| .:
Mouse   191 --------CFGDDIEE-LPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGVPN--ERP-AR 243

  Fly   388 YRHDENILASKPLQLRQIESMFGGSQDFVTDDGLIIPTIPAYVRNKIEISADKAGLSLQRQIDIL 452
            ||||||||.|:|:..|:|......|::|.||.||::|::...:..|:...|:|.||:|:|::::.
Mouse   244 YRHDENILESEPIVYRRITVPHSVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMT 308

  Fly   453 ARGASDLAITLLGGARRLTPANNHQWPKIAIICDGGKNMRTINIGAATGRQLASHGLTVLLYVEQ 517
            ...||.:|:|||||..||.|.|.||.|.:|::|  |.:::... |.:.||.||:|.:.|:|::..
Mouse   309 GVCASQMALTLLGGPNRLNPKNVHQRPTVALLC--GPHVKGAQ-GISCGRHLANHDVQVILFLPN 370

  Fly   518 -AKLLEQNSSSPEISLFKATDNVIVHSVDALPTP--DLVILSTN---TANLSD-----AIRKWLS 571
             .|:||  |.:.|:|||..|....|.|:..||..  ||||...:   .|.|.|     |...|.:
Mouse   371 FVKMLE--SITNELSLFSKTQGQQVSSLRDLPASPVDLVINCLDCPENAFLRDQPWYKAAVAWAN 433

  Fly   572 VNRASVLAIDPPPCGINEVAIKYSILPILPLNGISTATTSSSSSAAATPTPIASTSAAASATKSA 636
            .|||.||:||||   ::||.           .||.    :..|.|...|.|:.
Mouse   434 QNRAPVLSIDPP---VHEVE-----------QGID----AKWSLALGLPLPLG------------ 468

  Fly   637 ASTNNCGKLYLCNLGIPDKFYRD 659
               .:.|::|||::|||.:.:::
Mouse   469 ---EHAGRVYLCDIGIPQQVFQE 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edc3	NP_648992.1	LSm16_N	5..69	CDD:212484	23/67 (34%)
		FDF	343..>397	CDD:286601	26/53 (49%)
		YjeF_N	453..583	CDD:294225	55/140 (39%)
Edc3	XP_036010982.1	LSm16_N	4..66	CDD:212484	23/67 (34%)
		Edc3_linker	102..197	CDD:406897	12/95 (13%)
		FDF	200..300	CDD:370547	17/99 (17%)
		YjeF_N	302..455	CDD:397779	54/154 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846157
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0062
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11827
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3413
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006369
OrthoInspector	1	1.000	-	-		oto91917
orthoMCL	1	0.900	-	-		OOG6_106564
Panther	1	1.100	-	-	LDO	PTHR13612
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6031
SonicParanoid	1	1.000	-	-		X6088
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.780