Protein Alignment Edc3 and Edc3

DIOPT Version :9

• Sequence 1: NP_648992.1
• Gene: Edc3 / 39957
• FlyBaseID: FBgn0036735
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_002729954.2
• Gene: Edc3 / 315708
• RGDID: 1306898
• Length: 506
• Species: Rattus norvegicus
• Alignment Length: 691
• Identity: 195/691 - (28%)
• Similarity: 297/691 - (42%)
• Gaps: 206/691 - (29%)

  Fly     7 DWIGCAVSIACDEVLGVFQGLIKQIS--AEEITIVRAFRNG----VPLRKQNAEVVLKCTDIRSI 65
            ||:|..|||.|.:.|||:||.:..:.  ::.|::.|.|.||    ||      ||..:..||..:
  Rat     2 DWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVP------EVTFRAGDITEL 60

  Fly    66 DLIEPAKQDLDGHTAPPPVVNKPTPVKLPHFSNILGKQQQLQLQQQQQQLQLQQQQKQQFQEQER 130
            .::|          .|.|..|                                    |||
  Rat    61 KILE----------IPGPGDN------------------------------------QQF----- 74

  Fly   131 EQDLPSTPRSRANDNGRVAAGGASSSSGPRGNFNSALSDKMHQLKLIETNGSNGTLRTPQTSRAS 195
             .||..|                  ..||.|        ..:|:. |..||:...::.|.:|
  Rat    75 -GDLHQT------------------ELGPSG--------VGYQMS-INQNGTGKVVKKPASS--- 108

  Fly   196 SAQQQPQISTTPNSVAAFFGNMIPPKVEVKLGSYVSNTRESYCSSSGDSGEATGLSLGSSKPIDI 260
                    |:.|.|        ||.:.::|......:.::..||.|........||...|
  Rat   109 --------SSAPQS--------IPKRTDMKSQDVAISPQQQQCSKSYVDRHMESLSQSKS----- 152

  Fly   261 VSNGDGFYKQTAASSYGNTNGNVRRNGNANNNGNGTGNGSYTNGNG--NGNGKNKRNRVRRESSM 323
                                  .||..|:.::.:...|.:....:|  ||..|||.:.
  Rat   153 ----------------------FRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDE------- 188

  Fly   324 RQQQVQLTFGSEADDPLIHEDFDFEGNLALFDKQAIWDDIESTTQKPDVVRHIVNNHHHKPEQKY 388
                   .||.:.:: :...|||||||||||||.|::::|::..::.......|.|  .:| .:|
  Rat   189 -------CFGDDIEE-IPDTDFDFEGNLALFDKAAVFEEIDTYERRSGSRSRGVPN--ERP-ARY 242

  Fly   389 RHDENILASKPLQLRQIESMFGGSQDFVTDDGLIIPTIPAYVRNKIEISADKAGLSLQRQIDILA 453
            |||||||.|:|:..|:|......|::|.||.||::|::...:..|:...|:|.||:|:|::::..
  Rat   243 RHDENILESEPIVYRRITVPHSVSKEFCTDSGLVVPSVSYELHKKLLSVAEKHGLTLERRLEMTG 307

  Fly   454 RGASDLAITLLGGARRLTPANNHQWPKIAIICDGGKNMRTINIGAATGRQLASHGLTVLLYVEQ- 517
            ..||.:|:|||||..||.|.|.||.|.:|::|  |.:::... |.:.||.||:|.:.|:|::..
  Rat   308 VCASQMALTLLGGPNRLNPKNVHQRPTVALLC--GPHVKGAQ-GISCGRHLANHDVQVILFLPNF 369

  Fly   518 AKLLEQNSSSPEISLFKATDNVIVHSVDALPTP--DLVILSTN---TANLSD-----AIRKWLSV 572
            .|:||  |.:.|:|||..|....|.|:..|||.  ||||...:   .|.|.|     |...|.:.
  Rat   370 VKMLE--SITNELSLFSKTQGQQVSSLRDLPTSPVDLVINCLDCPENAFLRDQPWYKAAVAWANQ 432

  Fly   573 NRASVLAIDPPPCGINEVAIKYSILPILPLNGISTATTSSSSSAAATPTPIASTSAAASATKSAA 637
            |||.||:||||   ::||.           .||.    :..|.|...|.|:.
  Rat   433 NRAPVLSIDPP---VHEVE-----------QGID----AKWSLALGLPLPLG------------- 466

  Fly   638 STNNCGKLYLCNLGIPDKFYRDCGIKYKSPYGHKYVIPIHS 678
              .:.|::|||::|||.:.:::.||.|.||:|.|:|||:||
  Rat   467 --EHAGRVYLCDIGIPQQVFQEVGIDYHSPFGCKFVIPLHS 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edc3	NP_648992.1	LSm16_N	5..69	CDD:212484	23/67 (34%)
		FDF	343..>397	CDD:286601	26/53 (49%)
		YjeF_N	453..583	CDD:294225	56/140 (40%)
Edc3	XP_002729954.2	LSm16_N	2..64	CDD:212484	23/67 (34%)
		Edc3_linker	100..195	CDD:293206	15/94 (16%)
		FDF	197..298	CDD:286601	16/100 (16%)
		YjeF_N	300..453	CDD:281800	53/154 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349618
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0062
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11827
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3337
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412946at33208
OrthoFinder	1	1.000	-	-		FOG0006369
OrthoInspector	1	1.000	-	-		oto95492
orthoMCL	1	0.900	-	-		OOG6_106564
Panther	1	1.100	-	-	LDO	PTHR13612
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6088
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.760