Protein Alignment Edc3 and Edc3

DIOPT Version :10

• Sequence 1: NP_648992.1
• Gene: Edc3 / 39957
• FlyBaseID: FBgn0036735
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_312817.5
• Gene: Edc3 / 1273803
• VectorBaseID: AGAMI1_002216
• Length: 547
• Species: Anopheles gambiae
• Alignment Length: 698
• Identity: 258/698 - (36%)
• Similarity: 341/698 - (48%)
• Gaps: 184/698 - (26%)

  Fly     8 WIGCAVSIACDEVLGVFQGLIKQISAEEITIVRAFRNGVPLRKQNAEVVLKCTDIRSIDLIEPAK 72
            |:|.:|||.|...:|:|||:||:::...:.|.:|.|||:||:|.|.||.|...||..:|||..:.
Mosquito     5 WVGKSVSIHCRNDIGIFQGIIKRVTPSVVVITKAVRNGIPLKKNNVEVTLSAVDIAKLDLISCSN 69

  Fly    73 QDLDGHTAPPPVVNKPTPVKLPHFSNILGKQQQ---LQL-----QQQQQQLQLQQQQKQQFQEQE 129
                    .|.:.:||......:...:.....|   |:|     |.||||   ||||:||||
Mosquito    70 --------VPSIPSKPVATVAANSGMVTSLDDQYDGLKLMNNGKQHQQQQ---QQQQQQQFQ--- 120

  Fly   130 REQDLPSTPRSRANDNGRVAAGGASSSSGPRGNFNSALSDKMHQLKLIETNGSNGTLRTPQTSRA 194
                                                              ||:....:.     |
Mosquito   121 --------------------------------------------------NGTGSAFKL-----A 130

  Fly   195 SSAQQQPQISTTPNSVAAFFGNMIPPKVEVKLGSYVSNTRESYCSSSGDSGEATGLSLGSSKPID 259
            :.:..|.:.:.|||       |...|.|                        ..|.|..||.|||
Mosquito   131 TKSPAQSKYANTPN-------NTTQPVV------------------------GQGKSTASSHPID 164

  Fly   260 IVSNGDGFYKQTAASSYGNTNGNVRRNGNANNNGNGTG-----------NGSYTNGNGNGNGKNK 313
            | :||..  :...|||:  |.|.|      .:.|||..           :||.....||||||..
Mosquito   165 I-NNGSA--QNHMASSF--TGGFV------GSFGNGRPVATVSQSLPHVDGSAKKNGGNGNGKTS 218

  Fly   314 RNR--VRRESSMRQQQVQLTFGSEADDPLIHE-DFDFEGNLALFDKQAIWDDIES-TTQKPDVVR 374
            |:|  :.::|         ||||..||||..| |||||.|||||||||||::|:: .|:..:...
Mosquito   219 RSRKNLAKDS---------TFGSPDDDPLEMEGDFDFEKNLALFDKQAIWNEIDAHQTKASEAAA 274

  Fly   375 HIVNNHHHKPEQKYRHDENILASKPLQLRQIESMFGGS---QDFVTDDGLIIPTIPAYVRNKIEI 436
            ...|......:.|||||||:|.|.|.|.|||......|   |::|||:||:||:|||.:|:.:|.
Mosquito   275 RQRNAPSSAAKTKYRHDENVLVSTPAQYRQIVVQRVASRDAQEYVTDEGLVIPSIPATLRHTVEE 339

  Fly   437 SADKAGLSLQRQIDILARGASDLAITLLGGARRLTPANNHQWPKIAIICDGGKNMRTINIGAATG 501
            .|...|||.:||.|.|||||::||:.||||:|||||.|.||||||.|:|:|    :...:|.:|.
Mosquito   340 YAVSMGLSRERQHDFLARGATELALQLLGGSRRLTPNNQHQWPKIVIVCEG----KLDEVGISTA 400

  Fly   502 RQLASHGLTVLLYVEQAKLLEQNSSSPEISLFKATDNVIVHSVDALPTPDLVILSTNTANLSDAI 566
            ||||||||..::|:  ..|.|...:|.|:.|:.||.|.|...|:.||..||||.|.....|:|.:
Mosquito   401 RQLASHGLETVVYL--CSLTEATQNSSEVPLYMATGNKISVDVNTLPPCDLVIASVQNPRLTDQL 463

  Fly   567 RKWLSVNRASVLAIDPPPCGINEVAIKYSILPILPLNGISTATTSSSSSAAATPTPIASTSAAAS 631
            |||:|.:||.|||||||..|:..|:||.||||||||:||.
Mosquito   464 RKWISYSRAPVLAIDPPGAGLEGVSIKCSILPILPLDGID------------------------- 503

  Fly   632 ATKSAASTNNCGKLYLCNLGIPDKFYRDCGIKYKSPYGHKYVIPIHSK 679
                  ..:.||:|||||||||::.:|..||.||||: .|:|||||.:
Mosquito   504 ------QNDACGRLYLCNLGIPNQIFRRAGITYKSPF-DKFVIPIHRR 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edc3	NP_648992.1	LSm16_N	5..69	CDD:212484	28/60 (47%)
		FDF	343..>397	CDD:430668	28/55 (51%)
		YjeF_N	453..583	CDD:444831	66/129 (51%)
Edc3	XP_312817.5	None