Protein Alignment Edc3 and edc3

DIOPT Version :10

• Sequence 1: NP_648992.1
• Gene: Edc3 / 39957
• FlyBaseID: FBgn0036735
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001120062.1
• Gene: edc3 / 100145060
• XenbaseID: XB-GENE-5890820
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 712
• Identity: 189/712 - (26%)
• Similarity: 283/712 - (39%)
• Gaps: 251/712 - (35%)

  Fly     7 DWIGCAVSIACDEVLGVFQGLIKQIS--AEEITIVRAFRNG----VPLRKQNAEVVLKCTDIRSI 65
            ||:|..|||.|...|||:||.:..:.  .:.|::.:.|.||    ||      ||..:..||..:
 Frog     4 DWLGSIVSINCGNTLGVYQGCVSAVDHINQTISLTQPFHNGVKCLVP------EVTFRAGDISEL 62

  Fly    66 DLIEPAKQDLDGHTAPPPVVNKPTPVKLPHFSNILGKQQQLQLQQQQQQLQLQQQQKQQFQEQER 130
            .::|
 Frog    63 KILE------------------------------------------------------------- 66

  Fly   131 EQDLPSTPRSRANDNGRVAAGGASSSSGPRGNFNSALSDKMHQLKLIETNGSNGTLRTPQTSRAS 195
               :||......:|.                     |:|.......:.:...|||.:...|...|
 Frog    67 ---IPSESLKFTSDQ---------------------LNDHSTGFGYLPSRQQNGTSKQKPTVAQS 107

  Fly   196 SAQQQPQISTTPNSVAAFFGNMIPPKVEVKLGSYVSNTRESYCSSSGDSGEATGLSLGSSKPIDI 260
            :||.                  ||.:.|                     |:||..|  ||.|
 Frog   108 TAQN------------------IPGREE---------------------GKATEPS--SSSP--- 128

  Fly   261 VSNGDGFYKQTAASSY-------GNTNGNVRRNGNANNNGNGTGNGSYTNGNGNGNGKNKRNRVR 318
                     |..:.||       .|...|.||..|:.::.:...|......:|..||:.|
 Frog   129 ---------QPCSKSYIDRHSEAVNQPKNFRRRHNSWSSSSRYPNQVTPKKSGTKNGQMK----- 179

  Fly   319 RESSMRQQQVQLTFGSEADDPLIHEDFDFEGNLALFDKQAIWDDIESTTQKPDVVRHIVNNHHHK 383
                .|..:   .||.:.:: :...|||||||||||||.|::::|::              |..:
 Frog   180 ----ARDDE---CFGDDLEE-IPDTDFDFEGNLALFDKAAVFEEIDT--------------HERR 222

  Fly   384 -----------PEQK---YRHDENILASKPLQLRQIESMFGGSQDFVTDDGLIIPTIPAYVRNKI 434
                       |.::   ||||||||.|:|:..|:|.....|.:::.||.||::|:|...:..|:
 Frog   223 GGGGGARSRGTPNERPPTYRHDENILESEPIVYRKIVVPQSGGKEYCTDSGLVVPSISYVLHKKL 287

  Fly   435 EISADKAGLSLQRQIDILARGASDLAITLLGGARRLTPANNHQWPKIAIICDGGKNMRTINIGAA 499
            ...|:|.|||::|:::|....||.:|:|||||..||.|.|.||.|.:|::|  |.:::... |.:
 Frog   288 LCVAEKHGLSVERRLEISGVCASQMALTLLGGPNRLNPKNVHQRPTVALLC--GPHVKGAQ-GIS 349

  Fly   500 TGRQLASHGLTVLLYVEQ-AKLLEQNSSSPEISLFKATDNVIVHSVDALP--TPDLVI--LSTN- 558
            .||.||:|.:.::|::.. .|:||..::  |::||..|....|.||..||  ..||||  |..|
 Frog   350 CGRHLANHDVDIILFLPNFVKMLEPVTN--ELNLFCQTQGKQVSSVKDLPECPVDLVINCLDCNE 412

  Fly   559 TANLSD-----AIRKWLSVNRASVLAIDPPPCG--INEVAIKYSILPILPLNGISTATTSSSSSA 616
            .:.|.|     |...|.:.|||.||.|| ||.|  :..:..|:|:...|||
 Frog   413 NSFLRDQPWYRAAVDWANQNRAPVLNID-PPVGDHVQGIHAKWSLELGLPL-------------- 462

  Fly   617 AATPTPIASTSAAASATKSAASTNNCGKLYLCNLGIPDKFYRDCGIKYKSPYGHKYVIPIHS 678
                                |.....|::|||::|||.|.:|:.||.|.||:|.|:|||:||
 Frog   463 --------------------ALGEQAGRIYLCDIGIPQKVFREAGISYHSPFGCKFVIPLHS 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Edc3	NP_648992.1	LSm16_N	5..69	CDD:212484	22/67 (33%)
		FDF	343..>397	CDD:430668	25/67 (37%)
		YjeF_N	453..583	CDD:444831	54/140 (39%)
edc3	NP_001120062.1	LSm16_N	2..66	CDD:212484	22/67 (33%)
		Edc3_linker	98..188	CDD:465188	29/154 (19%)
		FDF	192..297	CDD:430668	40/119 (34%)
		YjeF_N	298..462	CDD:427546	62/169 (37%)