DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7564 and usp106

DIOPT Version :9

Sequence 1:	NP_001261989.1	Gene:	CG7564 / 39956	FlyBaseID:	FBgn0036734	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_588000.1	Gene:	usp106 / 2539055	PomBaseID:	SPCC16A11.13	Length:	264	Species:	Schizosaccharomyces pombe

Alignment Length:	296	Identity:	99/296 - (33%)
Similarity:	157/296 - (53%)	Gaps:	61/296 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QMRAMLDQLMGTT-RNGDERQL-KFSDPRVCKSFLLDCCPHDILASTRMDLGECPKVHDLAFRAD 75
            :.|.:::||||:. .|...|.| .|:|.:||:|||...|||||..:|:||||.|||:|....::|
pombe     4 EQRKIIEQLMGSNLSNFTSRGLVHFTDRKVCRSFLCGICPHDIFTNTKMDLGPCPKIHSDKLKSD 68

  Fly    76 YESAAKTRDYYYDIEAMEHLQAFIADCDRRTDSAKQRLKETQE------ELTAEVAEKANAVHGL 134
            ||.|:.:.||.|:.:.:|.|:..:.||::|.|.|:.|.::|:|      ||..::....:::..:
pombe    69 YERASYSHDYGYEWDYLEDLERHVDDCNKRIDIAEARREKTKEEEERIDELMRDIIHTDHSIEVI 133

  Fly   135 AEEIGKKLAKAEALGEAGEVEDSMELMKEIEELRA--KKIKAEHEYRTSMP--ASTYQQQKLRVC 195
            ..|:       |||.:...|.|:::...|:..|:.  |::..|......:|  ||| ..|||:||
pombe   134 ITEM-------EALAKRKLVNDAVKHFIELNRLKTYRKELYDEVISMNEIPSQAST-THQKLQVC 190

  Fly   196 EVCSAYLGIHDNDIRLADHFGGKLHLGFLTIREKLIELEKTAAPRKAELKRTGKMTDREDEGRGR 260
            ::|||||...|||.||||||.||:|||:..:|       ..|...:|:|:      |||
pombe   191 DICSAYLSRLDNDRRLADHFSGKMHLGYAMLR-------NIARDLRAQLE------DRE------ 236

  Fly   261 NRYFVGGRELDRRSRVHRSRSRERQRNRDGDRERPN 296
                               :||::   :||:::|.|
pombe   237 -------------------KSRDK---KDGEKQRDN 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7564	NP_001261989.1	LUC7	11..248	CDD:227527	90/246 (37%)
CG7564	NP_001261989.1	LUC7	12..246	CDD:281222	90/244 (37%)
usp106	NP_588000.1	LUC7	1..264	CDD:227527	99/296 (33%)
usp106	NP_588000.1	LUC7	3..245	CDD:281222	96/289 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1100
eggNOG	1	0.900	-	-		E1_COG5200
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I1288
OMA	1	1.010	-	-		QHG55077
OrthoFinder	1	1.000	-	-		FOG0001856
OrthoInspector	1	1.000	-	-		oto100423
orthoMCL	1	0.900	-	-		OOG6_103514
Panther	1	1.100	-	-	LDO	PTHR12375
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2181
SonicParanoid	1	1.000	-	-		X1216
TreeFam	1	0.960	-	-
	13	12.860