| Sequence 1: | NP_648990.1 | Gene: | U4-U6-60K / 39955 | FlyBaseID: | FBgn0036733 | Length: | 553 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004688.2 | Gene: | PRPF4 / 9128 | HGNCID: | 17349 | Length: | 522 | Species: | Homo sapiens |
| Alignment Length: | 548 | Identity: | 276/548 - (50%) |
|---|---|---|---|
| Similarity: | 367/548 - (66%) | Gaps: | 48/548 - (8%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 4 DDDIQYIKRQRTLHYGSLEESERKRQNAAASGAAATTTSGTTASSGAGTTTTGTGGQLEDIDSDE 68
Fly 69 DYEESTKKTSNAKQAGAPPPTAATLANKIDDDYFDLEMEMERDKVALLEEFERKKRARQINVSTD 133
Fly 134 DTEIKSNLRQLNEPICYFGEGPAERRRRLKELLAGLGENAINKRQYEDEERKQQQREQDQATWYH 198
Fly 199 EGPDSLRIARLWLADYSLPRAKDRLVRAREALEVPSAARAGRMVEMQKKLQSLAPLCSQVGDTRP 263
Fly 264 VSSAAFSEDSSLLLTSSWSGLCKLWSVPDCELKQTLRGHASYVGGVALRP--GVKADEENVVAMA 326
Fly 327 SGGHDGAVKLWGFNNEESIADITGHMPHRVSKVAFHPSGRFLATACYDSSWRLWDLEQKTEVLHQ 391
Fly 392 EGHAKPVHCLSYHSDGSVLVTGGLDAFGRVWDLRTGRCIMFLEGHLGAVFGVDFSPNGFHIATGS 456
Fly 457 QDNTCKIWDLRRRQPVYTIPAHTNLISDVKYQQECGSFLVTCSYDSTTKIWSNKTWQPLKTLQGH 521
Fly 522 DNKVISVDIAPNSQYIATTSFDRTFKLW 549 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| U4-U6-60K | NP_648990.1 | SFM | 132..>166 | CDD:128776 | 22/33 (67%) |
| WD40 repeat | 264..301 | CDD:293791 | 22/36 (61%) | ||
| WD40 | <286..553 | CDD:225201 | 161/266 (61%) | ||
| WD40 | 286..550 | CDD:238121 | 161/266 (61%) | ||
| WD40 repeat | 357..393 | CDD:293791 | 24/35 (69%) | ||
| WD40 repeat | 398..434 | CDD:293791 | 26/35 (74%) | ||
| WD40 repeat | 441..476 | CDD:293791 | 25/34 (74%) | ||
| WD40 repeat | 482..519 | CDD:293791 | 17/36 (47%) | ||
| WD40 repeat | 525..551 | CDD:293791 | 15/25 (60%) | ||
| PRPF4 | NP_004688.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..20 | 1/1 (100%) | |
| SFM | 103..141 | CDD:128776 | 23/37 (62%) | ||
| WD 1 | 229..268 | 24/38 (63%) | |||
| WD40 | 233..519 | CDD:238121 | 171/287 (60%) | ||
| WD40 repeat | 234..271 | CDD:293791 | 22/36 (61%) | ||
| WD 2 | 271..318 | 17/47 (36%) | |||
| WD40 repeat | 285..321 | CDD:293791 | 15/36 (42%) | ||
| WD 3 | 321..360 | 25/39 (64%) | |||
| WD40 repeat | 326..362 | CDD:293791 | 24/35 (69%) | ||
| WD 4 | 363..402 | 26/38 (68%) | |||
| WD40 repeat | 369..404 | CDD:293791 | 25/34 (74%) | ||
| WD 5 | 405..444 | 26/38 (68%) | |||
| WD40 repeat | 410..444 | CDD:293791 | 23/33 (70%) | ||
| WD 6 | 447..487 | 19/39 (49%) | |||
| WD40 repeat | 452..489 | CDD:293791 | 17/36 (47%) | ||
| WD 7 | 490..521 | 18/30 (60%) | |||
| WD40 repeat | 495..519 | CDD:293791 | 13/23 (57%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165146569 | |
| Domainoid | 1 | 1.000 | 101 | 1.000 | Domainoid score | I7009 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0272 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H3446 | |
| Inparanoid | 1 | 1.050 | 549 | 1.000 | Inparanoid score | I1147 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S1130 |
| OMA | 1 | 1.010 | - | - | QHG54420 | |
| OrthoDB | 1 | 1.010 | - | - | D1076587at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0004342 | |
| OrthoInspector | 1 | 1.000 | - | - | oto90484 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102752 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR19846 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1883 |
| SonicParanoid | 1 | 1.000 | - | - | X3609 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 17 | 16.750 | |||||