Protein Alignment U4-U6-60K and CG7568

DIOPT Version :10

• Sequence 1: NP_648990.1
• Gene: U4-U6-60K / 39955
• FlyBaseID: FBgn0036733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001263071.1
• Gene: CG7568 / 43482
• FlyBaseID: FBgn0039673
• Length: 482
• Species: Drosophila melanogaster
• Alignment Length: 367
• Identity: 99/367 - (26%)
• Similarity: 166/367 - (45%)
• Gaps: 44/367 - (11%)

  Fly   215 SLPRAKDRLVRAREALEVPSAARAGRMVEMQKKLQSLAPL--------CSQVGDTRPVSSAAFSE 271
            |:.|:::.....::|||           ::||||:.  |:        |.. ....|:::.:|..
  Fly    78 SVARSQNAFSALKQALE-----------KLQKKLRE--PVKKKFYLHKCHN-SHILPLTNVSFDR 128

  Fly   272 DSSLLLTSSWSGLCKLWSVPDCELKQTLRGHASYVGGVA---------LRPGVKADEENVVA--- 324
            .....||.|:...|.:.:....:::..|.||.:.|..|.         |:.|...:.....:
  Fly   129 SGERCLTGSYDRTCHVINTQTAQVEHILSGHDNVVFSVGFNFPHWLVYLQSGGSGNNLTTFSIIF 193

  Fly   325 ---MASGGHDGAVKLWGFNNEESIADITGHMPHRVSKVAFHP-SGRFLATACYDSSWRLWDLEQK 385
               :.:|..||..|:|...:.:|:....||....|: ..||| .|:.:|||..|.|.|::|:|..
  Fly   194 SDKIVTGSFDGTAKVWSATSGQSLCTFYGHTAELVA-AEFHPVDGKSIATASLDGSARIYDVETS 257

  Fly   386 TEVLHQEGHAKPVHCLSYHSDGSVLVTGGLDAFGRVWDLRTGRCIMFLEGHLGAVFGVDFSPNGF 450
            .|:.....|...|....::.||.:|:||..|....:||:|:......|.||...:....::.:|.
  Fly   258 HELQQLTHHGAEVIAARFNRDGQMLLTGSFDHSAAIWDVRSKSLGHQLRGHSAELSNCVWNFSGS 322

  Fly   451 HIATGSQDNTCKIWDLRR-RQPVYTIPAHTNLISDVKYQQECGSFLVTCSYDSTTKIW---SNKT 511
            .|||||.|||.:|||.|: .|.:|....|::.:.||.: ...|..|.|||.|.|.::|   .:..
  Fly   323 LIATGSLDNTARIWDTRKLDQELYLAARHSDEVLDVSF-DAAGQLLATCSSDCTARVWRLEGSSE 386

  Fly   512 WQPLKTLQGHDNKVISVDIAPNSQYIATTSFDRTFKLWSPDS 553
            .:.|..:.||.::|..|..:|:...:.|.|.|.|.:||..:|
  Fly   387 LEMLSLMAGHSDEVSKVCFSPSGCMLLTASADNTARLWLTES 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
U4-U6-60K	NP_648990.1	CCDC66	<113..>194	CDD:434558
		SFM	132..>166	CDD:128776
		WD40 repeat	264..301	CDD:293791	6/36 (17%)
		WD40	<286..553	CDD:441893	81/286 (28%)
		WD40 repeat	357..393	CDD:293791	13/36 (36%)
		WD40 repeat	398..434	CDD:293791	10/35 (29%)
		WD40 repeat	441..476	CDD:293791	15/35 (43%)
		WD40 repeat	482..519	CDD:293791	11/39 (28%)
		WD40 repeat	525..551	CDD:293791	9/25 (36%)
CG7568	NP_001263071.1	WD40	117..467	CDD:441893	88/314 (28%)
		WD40 repeat	122..158	CDD:293791	6/35 (17%)
		WD40 repeat	189..222	CDD:293791	6/32 (19%)
		WD40 repeat	228..265	CDD:293791	14/37 (38%)
		WD40 repeat	270..306	CDD:293791	10/35 (29%)
		WD40 repeat	314..348	CDD:293791	15/33 (45%)
		WD40 repeat	355..393	CDD:293791	11/38 (29%)
		WD40 repeat	400..436	CDD:293791	10/29 (34%)
		WD40 repeat	442..466	CDD:293791