Protein Alignment Oatp74D and Slco1a6

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_570092.1
• Gene: Slco1a6 / 84608
• RGDID: 69304
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 649
• Identity: 183/649 - (28%)
• Similarity: 305/649 - (46%)
• Gaps: 79/649 - (12%)

  Fly   168 RRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTY 232
            |.||...||::....||..:.:..||..|::|.||:.|.|.:...|::..:.|:|.:...:.::|
  Rat    14 RCFAKIKVFLLALTWAYASKALSATYMNSMLTQIERRFNISTSIVGLINGSFEVGNLLLIIFVSY 78

  Fly   233 FAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSE 297
            |..:.|||..|..|..:..:..|..:||||:.|.       ...:|.:||.:|..|
  Rat    79 FGRKRHRPIMIGIGCAVMGLGCFIISLPHFLMGR-------YEYETTISPTSNLSS--------- 127

  Fly   298 QVNPNLCILGGNQ----THSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGI 358
              |..||:....|    |...:||.:|.:         :::.:.:..|::: .|||:|.:..|||
  Rat   128 --NSFLCMENRTQTLKPTQDPAECVKEMK---------SLMWIYVLVGNII-RGIGETPIMPLGI 180

  Fly   359 PYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFSNPGFD-----ATDPRWIGAW 418
            .||:|...|:.||.|:.:....:|.||.:....||||...||:..:...|     .||.|.:|||
  Rat   181 SYIEDFAKSENSPFYIGILEVGKITGPIAAIWLGSFCATIYVDMGSVNTDDLTITPTDTRCVGAW 245

  Fly   419 WLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAPVEPEEKPKLKDFPKTVRRQLSNDI 483
            |:|.:....|.:|.||..|.|||.. .|:.|...    |...:.:|..|.::..|..:|.::.|.
  Rat   246 WIGFLVCAGLNILISIPFFFFPKTF-PKEGPEDM----ANETKNDEGDKHREKAKEEKRGITKDF 305

  Fly   484 LMF-RTASC-----------VFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGI 536
            .:| ::.||           |..:.....::||.|||||..:..::.:|..:.....:..:.:|.
  Rat   306 FLFMKSLSCNPIYMLCVLTSVLQVNGFVSIFTFKPKYLEHHYGKSSSEAIFLMGLYTLPSVCVGY 370

  Fly   537 VISGLFILKRKPTARGVAAWIAFTALVYSAGM------IILMFIGCSMNDFAGYKPS-DGNSPAL 594
            :||| ||:|:.......||:|:     |..||      :....:.|.....||...| :|...:.
  Rat   371 LISG-FIMKKFKITLKKAAFIS-----YCLGMSECLLSLCNFMLTCDNVPIAGLTTSYEGIQQSF 429

  Fly   595 -IEPTCSAALN--CTCDKENFAPICAD-GKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDA-- 653
             :|.|..|..|  |:|..:.:.|:|.| |..||:.|.|||..|.  .|....:..||:||..:
  Rat   430 DMENTVLADCNTRCSCLTKTWDPVCGDNGLAYITPCLAGCEKSV--GSGINMVLQDCSCIQSSGN 492

  Fly   654 PEAVNGYCDN--NCKNFI-YFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGL 715
            ..||.|.|:.  :|.|.: ||::|...|.|.:|.|.:...::.:||...::|::.:|:....:.:
  Rat   493 SSAVLGLCNKGPDCANKLQYFLIITVFCSFFYSLSLIPGYMIFLRCMKSEEKSLGIGLQAFCMRI 557

  Fly   716 FGNVPCPIIYGAVVDSACLIW-KSVCGKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWR 778
            .|.:..||.:|.::|..||.| ...||:.|||..|:.::||..:||:.|.:...::|....:.|
  Rat   558 LGGILAPIYFGVLIDRTCLHWGTQKCGEPGACRTYEINSFRSIYLGLPAALRGSSYLPAFFILR 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	173/616 (28%)
Slco1a6	NP_570092.1	oat	1..625	CDD:273279	183/649 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..295		3/22 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	647..670

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820