Protein Alignment Oatp74D and slco1f4

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001074135.2
• Gene: slco1f4 / 791184
• ZFINID: ZDB-GENE-070112-2172
• Length: 644
• Species: Danio rerio
• Alignment Length: 665
• Identity: 197/665 - (29%)
• Similarity: 308/665 - (46%)
• Gaps: 80/665 - (12%)

  Fly   144 DLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIK 208
            :.:||:...|.:.|    |        :|..:|:.....:|..:.|..:|..|.||.|||.|:|.
Zfish     9 EYSGGNQKTSQTKC----C--------SSLKIFICALAFSYFSKSMTGSYTKSTITQIEKRFEIP 61

  Fly   209 SKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSV 273
            |.|.|.:..:.|||.:....|::|...:.|||:.|..|::|..|.....|.|||:.|.
Zfish    62 SSTVGFIDGSFEMGNMLVITLVSYIGAKFHRPKIIGAGVLLMGIGTLLMASPHFLMGR------- 119

  Fly   274 ILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCI 338
            ....|..:..|::.:...::..|......|     .|..||  |    |.|:|..|...|||:
Zfish   120 YKYGTAATHTNDAGNFTVISTCSSDSQETL-----QQPFSG--C----QKEEAESSPFWVIVV-- 171

  Fly   339 FFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNF- 402
             .|:.: .|||:.::..||:.:|||....:.|..|:.....::.:||..|::.||.|...||:|
Zfish   172 -LGNTM-RGIGEASIVPLGMSFIDDYARPENSAFYIGCLNTLKGIGPIFGYMLGSLCANLYVDFG 234

  Fly   403 ----SNPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPK------QLRGKQKPPGQTATPA 457
                .:......|.||:||||||.|..|.|.|||:...:..||      |:......|.|..|
Zfish   235 LVDQESVTITPQDSRWVGAWWLGYVVSGLLTLLAAFPFWFLPKVLPENSQISLLDNTPQQHKT-- 297

  Fly   458 APVEPEEKPKLKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANM 522
               .|.....:|||..|.:|.|:|.|.:...|..:......|.:.|:.|||||.||..:...||.
Zfish   298 ---TPSLTEIVKDFAPTFKRLLTNKIYILYLAYSIVAFNDFAIVATYTPKYLEQQFGQSASKANF 359

  Fly   523 IAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMF-IGCSMNDFAGYK- 585
            :.....|..:.:|:.:||| ::||.......:|.:....:|.:..:.:..| :.|...|.||..
Zfish   360 LIGVTSIPAVALGVFLSGL-MMKRFKWGLLASARVNLLTIVATVFLAVPFFALSCENLDIAGVTV 423

  Fly   586 PSDGNSPAL-----IEPTCSAALNCTCDKENFAPICAD-GKMYISACHAGCSSSSLRPSDNRTLY 644
            |..|::...     :.|:|:|  :|.|....:.|:|.: |..|||.|||||:|:  :.:.....:
Zfish   424 PYQGSTEVQGVTSDVLPSCNA--DCGCPDLQWDPVCGENGVTYISPCHAGCNST--QGAGRNMTF 484

  Fly   645 SDCACIPD------APEAVNGYC--DNNCKNFIYFIL-IFAICVFMHSTSEVGSMLLVMRCTHPK 700
            .||.||..      ...||.|.|  |..|...||..| :.::..|:.....:....:.:|...|:
Zfish   485 HDCRCIQSWGLSVGNSSAVLGQCSRDPKCNRMIYIYLGLQSLAFFLCGLGIIPFFTMSLRIVDPE 549

  Fly   701 DKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIW---KSVCGKHGACSLYDADTFRQYFLGIT 762
            .|::::|::..|:.:.|.:|.||.:||::||.||.|   || ||: |||.:||.:|||..|.|:|
Zfish   550 LKSLSVGMLLLAVRVLGGIPAPIYFGALIDSTCLKWGQNKS-CGR-GACRIYDIETFRFLFQGLT 612

  Fly   763 AGIMFLAFLMDLVVW 777
               |.|..|...::|
Zfish   613 ---MCLRVLACSLLW 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	181/609 (30%)
slco1f4	NP_001074135.2	OATP	28..604	CDD:281175	181/609 (30%)
		MFS	30..>412	CDD:119392	118/409 (29%)
		KAZAL_SLC21	439..491	CDD:238650	20/55 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920