Protein Alignment Oatp74D and slco3a1b

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_021333633.1
• Gene: slco3a1b / 570448
• ZFINID: ZDB-GENE-161017-34
• Length: 690
• Species: Danio rerio
• Alignment Length: 680
• Identity: 203/680 - (29%)
• Similarity: 321/680 - (47%)
• Gaps: 90/680 - (13%)

  Fly   134 SESEESDFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVI 198
            :|....|.:.|     ..:..:||            |::..:|::......:.||....|.|||:
Zfish     3 AEGSTPDTEPD-----ECQKKTSC------------FSNIKIFLISECALMLAQGTVGAYLVSVL 50

  Fly   199 TTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFI 263
            ||:|:.|.::|...|::.|:.|:|.:...:.::||..|.||||.|.||.::.::.|...|||.|
Zfish    51 TTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARAHRPRLIGCGGIVMALGALLSALPEF- 114

  Fly   264 FGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQV-NPN-LCILGGNQTHSGSECNEERQLEQA 326
                |.|.  ...||..|.|.....:...|:|...: :|. :|   ||:|:
Zfish   115 ----LTHQ--YQYQTGESRPVGQGQNVCSNSSRAGLSDPGYIC---GNRTN-------------- 156

  Fly   327 SHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIF 391
                 |.::..:..|:.:..|:|.|.:..||:.||||:|..:.|.:|:.:.....:.|||.|||.
Zfish   157 -----TNMMYLLLIGAQMLLGVGATPLQPLGVSYIDDHVRREDSSLYIGILFSTLVFGPACGFIL 216

  Fly   392 GSFCTRWYVN---FSNPGFDAT--DPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPG 451
            ||.||:.||:   ......|.|  |||||||||.|.:..|..:.::|..||.||:.|....:.||
Zfish   217 GSLCTKVYVDAVFIDTTTLDITPDDPRWIGAWWGGFIICGLFLFVSSFFMFGFPQSLNEPGEGPG 281

  Fly   452 ----QTATPAAPVEPEEKPKLKD----------------FPKTVRRQLSNDILMFRTASCVFHLL 496
                |...||..|:..|..|..|                .||..:..|||.:......:....:.
Zfish   282 GESEQAMLPAELVQEYEGVKTSDDLEISTGLTCCQHLQVIPKVTKHLLSNPVFTCVILAACMEIA 346

  Fly   497 PIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTA 561
            .:||...||.||||.||.|:|..||.:.....|....:||.:.||.:.|...:|.|.........
Zfish   347 VVAGFAAFLGKYLEQQFNLSTSSANQLLGMTAIPCACLGIFLGGLLVKKLDLSALGAIRLAMIVN 411

  Fly   562 LVYSAGMIILMFIGCSMNDFAGYKPSDGN-SPALIEPTCSAALN-CTCDKENFAPIC-ADGKMYI 623
            ::.:|..:..:|:||.....||...:.|| |....|.|.:|.|: |.|.|.:.:|:| ::|..|:
Zfish   412 IISTACYVSFLFLGCDTGPVAGVTVAYGNESLGSWERTEAACLSGCNCYKSSLSPVCGSNGVTYL 476

  Fly   624 SACHAGCSSSSLRPSDNRTLYSDCACIPDAP---EAVNGYCDN-NCKN-FIYFILIFAICVFMHS 683
            |||.|||:         ||..:.|.||..:.   .|..|.|.: .|:. |:.|:.:...|..:.:
Zfish   477 SACLAGCT---------RTNLTGCKCIAHSEGLGTATPGKCPSPGCQQAFLTFLAVVCACSMIGA 532

  Fly   684 TSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWKSVCGKHGACSL 748
            .::..|:::::|...|:.|:.|:||:...:.|.|.:|.|:|:|..:||.||:|.|:||..|||.|
Zfish   533 MAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGIGIDSTCLLWSSMCGIKGACML 597

  Fly   749 YDADTFRQYFLGITAGIMFLAFLMDLVVWR 778
            ||..|:|..::.|...:...||::..|.|:
Zfish   598 YDNVTYRYLYVSIAIVLKSSAFILYAVTWQ 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	190/613 (31%)
slco3a1b	XP_021333633.1	OATP	27..603	CDD:308646	190/613 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578743
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940