Protein Alignment Oatp74D and slco3a1a

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001038653.1
• Gene: slco3a1a / 569735
• ZFINID: ZDB-GENE-030131-8662
• Length: 701
• Species: Danio rerio
• Alignment Length: 696
• Identity: 201/696 - (28%)
• Similarity: 317/696 - (45%)
• Gaps: 105/696 - (15%)

  Fly   132 RSSESEESDFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVS 196
            ||||..:.|         ..:...||            |::..:|:|......:.||....|.||
Zfish     7 RSSEDPQRD---------DIKKKPSC------------FSNIKIFLVAECALMLAQGTVGAYLVS 50

  Fly   197 VITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPH 261
            |:||:|:.|.::|...|::.|:.|:|.:...:.::||..:.||||.|.||.::.::.|...|||.
Zfish    51 VLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGAKAHRPRLIGCGGIVMALGALLSALPE 115

  Fly   262 FIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQA 326
            |:..:.                  ..:..|    |:....::|   .|.:.:...|.....
Zfish   116 FLASQY------------------KITDTW----SKDQGRDVC---SNTSKADEPCGNRAN---- 151

  Fly   327 SHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIF 391
                 |.::..:..|:.:..|||.|.|..||:.||||:|..|.|.:|:.:.....:.|||.|||.
Zfish   152 -----TNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRKKDSSLYIGILFSTLVFGPACGFIL 211

  Fly   392 GSFCTRWYVN--FSNPGFDAT-------DPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQ 447
            ||.||.:||:  |    .|.|       |||||||||.|.:..|:|:..:::.||.||:.|..|:
Zfish   212 GSVCTNFYVDALF----IDTTQLNITPDDPRWIGAWWGGFLICGALLFFSALFMFGFPQSLPSKE 272

  Fly   448 K---PPGQTA-TPAAPVEPEEKPK---------------------LKDFPKTVRRQLSNDILMFR 487
            .   |..:.| .||:..:..||.|                     |:..||..:..|||.:....
Zfish   273 MEGVPESEQAMLPASLSQDFEKSKPSNGVVQNYQPNSNSLSCCQQLRVIPKVTKHLLSNPVFTCI 337

  Fly   488 TASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARG 552
            ..:....:..:||...||.||||.||.|.|..||.:.....|....:||.:.||.:.|...:|.|
Zfish   338 VLAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLNLSALG 402

  Fly   553 VAAWIAFTALVYSAGMIILMFIGCSMNDFAGYKPSDGNSPALI--EPTCSAALNCTCDKENFAPI 615
            .........|:.:|..:..:|:||.....||...:.||....:  .|......:|.|...:.:|:
Zfish   403 AIRMAMLVNLISTACYVSFLFLGCDTGPVAGVTVAYGNETLQVGQTPEAPCMSHCNCYTSSVSPV 467

  Fly   616 C-ADGKMYISACHAGCS---SSSLRPSDNRTLYSDCACIP---DAPEAVNGYCDN-NCKN-FIYF 671
            | ::|..|:|:|.|||:   |:.| |:......|.||||.   |...||.|.|.. .|:. |:.|
Zfish   468 CGSNGVTYLSSCFAGCTRAISTGL-PAPLSQNLSGCACISGYNDFATAVPGKCPRPGCQEAFLTF 531

  Fly   672 ILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIW 736
            :.:...|..:.:.::..|:::::|...|:.|:.|:||:...:.|.|.:|.|:|:||.:||.||.|
Zfish   532 LCVICGCSMIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFW 596

  Fly   737 KSVCGKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWRKAHR 782
            .:.||..|||.|||..|:|..::.:...:..:|||:....|....|
Zfish   597 SAECGVKGACLLYDNVTYRHLYISMAIVLKIMAFLLYTTTWHCLRR 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	186/623 (30%)
slco3a1a	NP_001038653.1	OATP	29..614	CDD:281175	186/623 (30%)
		MFS	35..>265	CDD:119392	80/267 (30%)
		KAZAL_SLC21	449..506	CDD:238650	19/57 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578744
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750