Protein Alignment Oatp74D and Slco1a1

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_058807.1
• Gene: Slco1a1 / 50572
• RGDID: 3700
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 643
• Identity: 185/643 - (28%)
• Similarity: 307/643 - (47%)
• Gaps: 62/643 - (9%)

  Fly   168 RRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTY 232
            |.|:...||::....|.:.:.:...|..|::|.||:.|.|.:...|::..:.|:|.:...:.::|
  Rat    14 RLFSKMKVFLLSLTCACLTKSLSGVYMNSMLTQIERQFDISTSVAGLINGSFEIGNLFFIVFVSY 78

  Fly   233 FAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSE 297
            |..:.|||..|..|.|:..:.....:||||..|.       ...:|.:||..|..|
  Rat    79 FGTKLHRPVVIGIGCVIMGLGCLLMSLPHFFMGR-------YEYETTISPTGNLSS--------- 127

  Fly   298 QVNPNLCILGGNQ----THSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGI 358
              |..||:....|    |...:||.:|.:         :::.:|:..|::: .|||:|.:..|||
  Rat   128 --NSFLCMENRTQTLKPTQDPAECVKEMK---------SLMWICVMVGNII-RGIGETPIVPLGI 180

  Fly   359 PYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFSNPGFD-----ATDPRWIGAW 418
            .||:|...|:.||:|:.:....::.||..|.:.||:|.:.||:..:...|     .:|.||:|||
  Rat   181 SYIEDFAKSENSPLYIGILEMGKVAGPIFGLLLGSYCAQIYVDIGSVNTDDLTITPSDTRWVGAW 245

  Fly   419 WLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAPVEP------EEKPKL-KDFPKTVR 476
            |:|.:....:.:|.||..|..||.|..|.:......|....||.      ||...: |||...::
  Rat   246 WIGFLVCAGVNILTSIPFFFLPKALPKKGQQENVAVTKDGKVEKYGGQAREENLGITKDFLTFMK 310

  Fly   477 RQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGL 541
            |...|.|.|....:.|..:......:||||||||.|:..:|.:|..:.....:..:.:|.:|.|.
  Rat   311 RLFCNPIYMLFILTSVLQVNGFINKFTFLPKYLEQQYGKSTAEAIFLIGVYSLPPICLGYLIGGF 375

  Fly   542 FILKRKPTARGVAAWIAFTALVYSAGMIILMF-IGCSMNDFAGYKPS-DGNSPAL-IEPTCSAAL 603
            .:.|.|.|.: .||::||...|:...:.:..| :.|.....||...| .|....| :|....|..
  Rat   376 IMKKFKITVK-KAAYLAFCLSVFEYLLFLCHFMLTCDNAAVAGLTTSYKGVQHQLHVESKVLADC 439

  Fly   604 N--CTCDKENFAPICAD-GKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDA--PEAVNGYCDN 663
            |  |:|....:.|:|.| |..|:|||.|||  .....:....::.||:||...  ..||.|.|..
  Rat   440 NTRCSCSTNTWDPVCGDNGVAYMSACLAGC--KKFVGTGTNMVFQDCSCIQSLGNSSAVLGLCKK 502

  Fly   664 --NCKNFI-YFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIY 725
              .|.|.: ||:::..|..|::|.:.:...::.:||...::|::.:|:....|.:|..:|.|:.:
  Rat   503 GPECANRLQYFLILTIIISFIYSLTAIPGYMVFLRCVKSEEKSLGVGLHTFCIRVFAGIPAPVYF 567

  Fly   726 GAVVDSACLIWKSV-CGKHGACSLYDADTFRQYFLGI---TAGIMFLAFLMDLVVWRK 779
            ||::|..||.|.:: ||:.|||.:||.::||..:||:   ..|..:|.....|::.||
  Rat   568 GALIDRTCLHWGTLKCGQRGACRMYDINSFRHIYLGLPIALRGSSYLPAFFILILMRK 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	174/606 (29%)
Slco1a1	NP_058807.1	oat	1..625	CDD:273279	183/641 (29%)
		MFS	40..>408	CDD:119392	112/396 (28%)
		KAZAL_SLC21	436..488	CDD:238650	18/53 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..670

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820