Protein Alignment Oatp74D and Gm5724

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001365611.1
• Gene: Gm5724 / 435927
• MGIID: 3643685
• Length: 670
• Species: Mus musculus
• Alignment Length: 678
• Identity: 191/678 - (28%)
• Similarity: 328/678 - (48%)
• Gaps: 79/678 - (11%)

  Fly   165 RWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAML 229
            |..|.|:...||::....|.:.:.:..::..|::..||:.|.:.:.|.|::..:..||.:...:.
Mouse    11 RGVRCFSKVKVFLLALTGACVSKSLTGSHMKSMLLQIERQFGLLTSTVGLITGSFSMGMLLVIIP 75

  Fly   230 LTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNA 294
            ::||..:.|||..|..|.:...:..|..:||||:.|.       ...:|.:||.:|..|:.:|..
Mouse    76 VSYFGTKLHRPIMIGVGCMFMGLGCFIISLPHFLMGR-------YEYETTISPTSNLSSNSFLCM 133

  Fly   295 SSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIP 359
            .    |.:|.:   ..|...:||..|.:         :::.:.:..|::: .|:|:||:..|||.
Mouse   134 E----NRSLTL---KPTQDTTECGREIK---------SLMWIYVLVGNII-RGMGETAIMPLGIS 181

  Fly   360 YIDDNVGSKQSPMYMAV-TIGMRILGPASGFIFGSFCTRWYVNFSNPGFD-----ATDPRWIGAW 418
            ||:|...|:.||:|:.: .||:.| ....|:..||||...||:..:...|     .||.||:|||
Mouse   182 YIEDFAKSENSPLYIGILEIGITI-SYWIGYSLGSFCANIYVDTDSGNTDDLTITPTDTRWVGAW 245

  Fly   419 WLGPVAIGSLMLLASIAMFSFPKQL--RGKQKPPGQTATPAAPVEPEEKPK------LKDFPKTV 475
            |:|.:....:..|.||..|.|||.|  .|.| ..|.....|...:..||.|      :|||...:
Mouse   246 WIGFLVCAGVNFLTSIPFFFFPKTLPKEGLQ-DNGDGTENAKEEKHREKAKKENQRIIKDFFPLM 309

  Fly   476 RRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGI------ 534
            :....|.|.|......|........:.:::|||||.|:..::.|.        :.:|||
Mouse   310 KNLSCNPIYMLYLLISVLQFNTFVSMVSYVPKYLEQQYGKSSADV--------LFIMGIYMLPPI 366

  Fly   535 --GIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFI-GCSMNDFAGYKPS-DG-NSPAL 594
              |.::.||.:.|.|.||: .||:|||...:....:.:..:: .|.....||...| :| ..|..
Mouse   367 CLGYLLGGLIMKKFKITAK-KAAYIAFCLSLTDYLLSLSNYMTNCDSFQVAGLTASYEGVQHPLH 430

  Fly   595 IEPTCSAALN--CTCDKENFAPICA-DGKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDA--P 654
            ::....|..|  |:|....:.|:|. :|..|:|||.|||..|.  .:....::.:|:||..:  .
Mouse   431 VDHEVLADCNTRCSCLTNTWDPVCGNNGLAYMSACLAGCEKSV--GNGINMVFQNCSCIRSSGNS 493

  Fly   655 EAVNGYCDN--NCKNFI-YFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLF 716
            .||.|.|:.  :|.|.: |||:||::.:|:.|.|.:...::::||..|::|::.:|:......:|
Mouse   494 SAVLGLCNKGPDCDNMLKYFIIIFSVKMFIFSLSSIPGYMVLLRCMKPEEKSLGVGLHTFCTKIF 558

  Fly   717 GNVPCPIIYGAVVDSACLIWKSV-CGKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWRKA 780
            ..:|.||.:||::|.|||.|.:: ||:..||.:||.::||..|.|:.|.:...::|..:.:.|..
Mouse   559 AGIPAPIYFGALIDRACLHWGTLKCGEKAACRIYDINSFRYLFFGLPAALTGSSYLPAVFLLRLM 623

  Fly   781 HRIDIAPEDPQEGGPASNGRTLEVSESK 808
            ....: |||       ::....|::|:|
Mouse   624 RTFQL-PED-------TDSPDTELAETK 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	175/612 (29%)
Gm5724	NP_001365611.1	oat	1..624	CDD:273279	185/649 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820