Protein Alignment Oatp74D and slco1f1

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_017210475.1
• Gene: slco1f1 / 405853
• ZFINID: ZDB-GENE-040426-2192
• Length: 638
• Species: Danio rerio
• Alignment Length: 668
• Identity: 207/668 - (30%)
• Similarity: 313/668 - (46%)
• Gaps: 86/668 - (12%)

  Fly   143 SDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQI 207
            ||.|   ...||::|    |.||       ..:|:......|..:.|..:|..|.||.|||.|:|
Zfish    11 SDRN---EKASSTTC----CSPR-------LKIFICALAFCYFSKSMTASYTKSTITQIEKRFEI 61

  Fly   208 KSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSS 272
            .|.|.|.:..:.|||.:....|::|...:.|||:.|..|::|..|.....|.|||:.|.....::
Zfish    62 TSSTVGFIDGSFEMGNMLVITLVSYVGAKFHRPKIIGAGVLLMGIGTLLMASPHFLMGRYKYGTA 126

  Fly   273 VILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQT--HSGSECNEERQLEQASHSKITVIV 335
                           ::|..:|.:..| .:.|.....:|  ...|||    |:.:|..|.:.|:|
Zfish   127 ---------------ATHTNDAGNFTV-ISTCSSDSQETLQQPYSEC----QIIEAESSLLWVVV 171

  Fly   336 LCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYV 400
            |   .|:.: .|||:.::..||:.:|||....:.|..|:.....:|.:||..|||.||.|...||
Zfish   172 L---LGNAM-RGIGEASIVPLGMSFIDDYARPENSAFYIGCLNTLRGIGPIFGFILGSLCANLYV 232

  Fly   401 NFSNPGFDAT-----DPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAPV 460
            :|.....::.     |.||:||||||.|..|.|.|||:...:..|:.|      |..:.|....
Zfish   233 DFDLVNQESVTITPQDSRWVGAWWLGFVVSGLLTLLAAFPFWFLPRAL------PENSQTSELD- 290

  Fly   461 EPEEKPK--------LKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLAT 517
            .|.|:.|        :|||..|.:|.|:|.|.:...|..:......|.:.|:.|||||.||..:.
Zfish   291 HPSEQHKTTPSLTEIIKDFAPTFKRLLTNKIYILYLAYSIVAFNDFAIVATYTPKYLEQQFGQSA 355

  Fly   518 YDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMNDFA 582
            ..||.:.....|..:.:||.:|||.:.:.|......|....||.:......:....:.|...|.|
Zfish   356 SKANFLIGVTCIPAVALGIFLSGLMMKRFKWGLLASARVNLFTGVTMLLLAVPFFALSCENLDVA 420

  Fly   583 GYK-PSDGNSPAL-----IEPTCSAALNCTCDKENFAPICAD-GKMYISACHAGCSSSSLRPSDN 640
            |.. |..|::...     :.|:|:|  :|.|....:.|:|.: |..|||.|||||:|:. ....|
Zfish   421 GVTVPYQGSTEVQGVISDVLPSCNA--DCGCPDLQWDPVCGENGVTYISPCHAGCNSTQ-GAGWN 482

  Fly   641 RTLYSDCACIPD------APEAVNGYC--DNNCKNFIY-FILIFAICVFMHSTSEVGSMLLVMRC 696
            :| :.||.||..      ...||.|.|  |.||...|| |:.:.::.:|::|...|..:...||.
Zfish   483 KT-FHDCRCIQSWGLSVGNSSAVLGQCSRDPNCNQMIYVFLGVQSLVLFVYSLGAVPFLTFSMRI 546

  Fly   697 THPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIW--KSVCGKHGACSLYDADTFRQYFL 759
            ..|:.||:::||:..:|.:.|.:|.||.:|.::|:.||.|  :..||: |||.:||.:|||..|.
Zfish   547 VDPEMKALSVGVLLLSIRVLGGIPAPIYFGGLIDTTCLKWGQRKSCGR-GACRIYDNETFRFLFQ 610

  Fly   760 GITAGIMFLAFLMDLVVW 777
            |:|.|:..||.   .|:|
Zfish   611 GMTIGLRVLAC---SVLW 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	187/611 (31%)
slco1f1	XP_017210475.1	OATP	29..605	CDD:281175	187/611 (31%)
		MFS	31..>413	CDD:119392	120/412 (29%)
		KAZAL_SLC21	440..492	CDD:238650	22/55 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920