Protein Alignment Oatp74D and slco1f1

DIOPT Version :10

• Sequence 1: NP_648989.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_073801947.1
• Gene: slco1f1 / 405853
• ZFINID: ZDB-GENE-040426-2192
• Length: 683
• Species: Danio rerio
• Alignment Length: 716
• Identity: 216/716 - (30%)
• Similarity: 327/716 - (45%)
• Gaps: 105/716 - (14%)

  Fly   117 AHEQAPLTGGYKLPPRSSESEESD-------------FDSDLNGGSSA---------ESSSSCGL 159
            |...||..|.::..|.|..|:.||             |...:.|.|:.         .||::|
Zfish     5 AVSSAPEPGKHQAQPVSLSSDNSDPPAVQPPRVEPLPFKFIMEGSSNGMEYSDRNEKASSTTC-- 67

  Fly   160 FGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQI 224
              |.||       ..:|:......|..:.|..:|..|.||.|||.|:|.|.|.|.:..:.|||.:
Zfish    68 --CSPR-------LKIFICALAFCYFSKSMTASYTKSTITQIEKRFEITSSTVGFIDGSFEMGNM 123

  Fly   225 CTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSS 289
            ....|::|...:.|||:.|..|::|..|.....|.|||:.|.....::               ::
Zfish   124 LVITLVSYVGAKFHRPKIIGAGVLLMGIGTLLMASPHFLMGRYKYGTA---------------AT 173

  Fly   290 HWLNASSEQVNPNLCILGGNQT--HSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTA 352
            |..:|.:..| .:.|.....:|  ...|||    |:.:|..|.:.|:||   .|:.: .|||:.:
Zfish   174 HTNDAGNFTV-ISTCSSDSQETLQQPYSEC----QIIEAESSLLWVVVL---LGNAM-RGIGEAS 229

  Fly   353 VATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFSNPGFDAT-----DP 412
            :..||:.:|||....:.|..|:.....:|.:||..|||.||.|...||:|.....::.     |.
Zfish   230 IVPLGMSFIDDYARPENSAFYIGCLNTLRGIGPIFGFILGSLCANLYVDFDLVNQESVTITPQDS 294

  Fly   413 RWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAPVEPEEKPK--------LK 469
            ||:||||||.|..|.|.|||:...:..|:.|      |..:.|.... .|.|:.|        :|
Zfish   295 RWVGAWWLGFVVSGLLTLLAAFPFWFLPRAL------PENSQTSELD-HPSEQHKTTPSLTEIIK 352

  Fly   470 DFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGI 534
            ||..|.:|.|:|.|.:...|..:......|.:.|:.|||||.||..:...||.:.....|..:.:
Zfish   353 DFAPTFKRLLTNKIYILYLAYSIVAFNDFAIVATYTPKYLEQQFGQSASKANFLIGVTCIPAVAL 417

  Fly   535 GIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMNDFAGYK-PSDGNSPAL---- 594
            ||.:|||.:.:.|......|....||.:......:....:.|...|.||.. |..|::...
Zfish   418 GIFLSGLMMKRFKWGLLASARVNLFTGVTMLLLAVPFFALSCENLDVAGVTVPYQGSTEVQGVIS 482

  Fly   595 -IEPTCSAALNCTCDKENFAPICAD-GKMYISACHAGCSSSSLRPSDNRTLYSDCACIPD----- 652
             :.|:|:|  :|.|....:.|:|.: |..|||.|||||:|:. ....|:| :.||.||..
Zfish   483 DVLPSCNA--DCGCPDLQWDPVCGENGVTYISPCHAGCNSTQ-GAGWNKT-FHDCRCIQSWGLSV 543

  Fly   653 -APEAVNGYC--DNNCKNFIY-FILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAI 713
             ...||.|.|  |.||...|| |:.:.::.:|::|...|..:...||...|:.||:::||:..:|
Zfish   544 GNSSAVLGQCSRDPNCNQMIYVFLGVQSLVLFVYSLGAVPFLTFSMRIVDPEMKALSVGVLLLSI 608

  Fly   714 GLFGNVPCPIIYGAVVDSACLIW--KSVCGKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVV 776
            .:.|.:|.||.:|.::|:.||.|  :..||: |||.:||.:|||..|.|:|.|:..||.   .|:
Zfish   609 RVLGGIPAPIYFGGLIDTTCLKWGQRKSCGR-GACRIYDNETFRFLFQGMTIGLRVLAC---SVL 669

  Fly   777 W 777
            |
Zfish   670 W 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_648989.1	OATP	175..754	CDD:460821	187/611 (31%)
slco1f1	XP_073801947.1	None