Protein Alignment Oatp74D and Oatp58Da

DIOPT Version :10

• Sequence 1: NP_648989.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 715
• Identity: 229/715 - (32%)
• Similarity: 360/715 - (50%)
• Gaps: 85/715 - (11%)

  Fly   111 SLSEKYAHEQAPLTGGYKLPPRSSESEESDFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHV 175
            ::|:| ..|.||          .:|:|..|      ||    ..:.||.:..:....:|||:.|:
  Fly    24 AISDK-ERESAP----------ENETEGED------GG----KDTYCGFWIFKGPSMQRFATEHM 67

  Fly   176 FMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRP 240
            :::::.||..:..|...||...|||:||.::|.:|.:||:...:::..:.||.:|.|:||..|||
  Fly    68 YVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRP 132

  Fly   241 RWIACGMVLFSIAAFSCALP---HFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPN 302
            ||:..|  |.:|.|| |.|.   ||::|.    ....||.|:      .|.......::::.:..
  Fly   133 RWMGIG--LLTIVAF-CLLTSSLHFLYGA----GEDALQLTR------EFGQVNETLTNQERDKK 184

  Fly   303 LCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIF-FGSLLSSGIGQTAVATLGIPYIDDNVG 366
            ||     |..:|....||          :.:.|..:| |.:.|.||:||....||||.|:|||..
  Fly   185 LC-----QPTAGGCVQEE----------VGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTS 234

  Fly   367 SKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFS-NPGFDATDPRWIGAWWLGPVAIGSLML 430
            ..::|..::::..:|:||||.|:...:.|.|.|:..: .|.....||||:||||||.:.:.::.|
  Fly   235 KAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEPTLEPLIGQEDPRWLGAWWLGWLVLAAITL 299

  Fly   431 LASIAMFSFPKQLRGKQKPPGQTATPAAPVE-PEEKPKLKDFPKTVRRQLSNDILMFRTASCVFH 494
            :::|.:|.|||||...:|...|......... |..:..|.|..|||::...|.:.::.|.:.:.:
  Fly   300 VSAILLFMFPKQLPSARKRRLQLKQDERKQSLPLNERSLADMMKTVKKLSKNKVYVYNTMASILY 364

  Fly   495 LLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAF 559
            .......:.|.|||:|||:|.:...|.|......:.....||:|||..|.|.||:||.:|||.|.
  Fly   365 FFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAI 429

  Fly   560 TALVYSAGMIILMFIGCSMNDFAGYKP--SDGNSPALIEPTCSAALNCTCDKENFAPIC-ADGKM 621
            ...|..||::..:.|||..:|......  |.|||       |||  :|.||..::||:| ||...
  Fly   430 VDFVTVAGILCYVAIGCEGSDRLNTLTTLSAGNS-------CSA--SCHCDYVHYAPVCSADNIT 485

  Fly   622 YISACHAGCSSSSLRPSD--NRTLYSDCACI--------PDAPEAVNGYCDNNCKN-FIYFILIF 675
            :|||||||||.   |..|  .||:|:.|.|:        |::..||:|.|..:|.| |:.|:.:.
  Fly   486 FISACHAGCSE---RTKDALGRTIYTGCECLGSSSLNSEPESQFAVDGTCPVDCFNEFLIFLGVM 547

  Fly   676 AICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWKSVC 740
            .....:.::|:..::||.:||..|.:|..|:|:...|..|.|.:|.||.:|.::|:.||:|...|
  Fly   548 CFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTC 612

  Fly   741 GKHGACSLYDADTFRQYFLGITAG-IMFLAFLMDLVVWRKAHRIDIAPEDPQEGGPASNGRTLEV 804
            ...|.|.|||..:.| |.|.::|. .:||...:::.||..|..:.|.  |.:|..|..:.:..||
  Fly   613 SNKGNCWLYDTKSMR-YALNLSAAFFIFLGGFLNIAVWYHAKNLKIF--DEEESSPKDSLKNKEV 674

  Fly   805  804
              Fly   675  674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_648989.1	OATP	175..754	CDD:460821	198/598 (33%)
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	198/598 (33%)