Protein Alignment Oatp74D and Oatp33Eb

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_609570.1
• Gene: Oatp33Eb / 34662
• FlyBaseID: FBgn0032435
• Length: 814
• Species: Drosophila melanogaster
• Alignment Length: 750
• Identity: 178/750 - (23%)
• Similarity: 300/750 - (40%)
• Gaps: 151/750 - (20%)

  Fly   142 DSDL-----NGGSSAESSSSCGLFG---CRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVI 198
            :|||     |..:..:.|..||:.|   ||....:::|....|::|..::..|||...:||  .:
  Fly     7 NSDLSQIAVNANNIPDDSVDCGIKGLGWCRGPGCQKYARLRTFILVLAISGTLQGACESYF--RV 69

  Fly   199 TTIEKLFQI--KSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALP- 260
            :..:..||.  .......||.||.:.|...|:...|:|...|..:|:...::|.::......:|
  Fly    70 SAKQASFQFGWNPLIVDWLLVASGLFQAVFALAFAYWADVYHPIKWLVGTLMLQAVTCVVAVIPS 134

  Fly   261 --HFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQL 323
              :|..|.|                          |....::.|:|.....|.       :...|
  Fly   135 IMNFADGNQ--------------------------AKDALLDANMCATSLAQF-------QRLTL 166

  Fly   324 EQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASG 388
            .:|..|.:|   |.:.|...|:.|:|..|..|||:.|||||..|:.||..:...:..|:.|..:|
  Fly   167 TEAQSSSLT---LAMLFVLQLALGMGGLAYYTLGVSYIDDNSLSQDSPAVIGAALAARVFGQQAG 228

  Fly   389 --FIFGSFCTRWYVNFSNPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPG 451
              .:.|       |..::.|           ||||.|.:...:.:.::.:..|||:|      |.
  Fly   229 SFLVLG-------VGLTHVG-----------WWLGWVILAPFIFVGAVLLGLFPKRL------PK 269

  Fly   452 QTATPAAP--VEPEEKPKL----------KDFPKTVRRQLSNDILMFRTAS--CVFHLLPIAGLY 502
            .....||.  :|.....:.          .||..:::|..:|.:|||...|  ||...:...||.
  Fly   270 TVIHQAAQRIIEQSSMRRFGSQFSTYMDDSDFWPSLKRLFNNRLLMFNLLSIMCVQSAVVNYGLQ 334

  Fly   503 TFLPKYLETQFRL---------ATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIA 558
            .  ..||:::|.|         |.:.:..::.|....||.:|::||||.|.|.|.:||.:.....
  Fly   335 E--ESYLQSRFFLPYNEQDGLAAEWRSAFVSYFLKPPVMALGMLISGLVISKAKLSARKITGINI 397

  Fly   559 FTALVYSAGMIILMFIGCSMNDFAGYKPSDGNSPALIEPTCSAALNCTCDKENFAPICADGK--M 621
            ..::...|..|.|:|:.|.:...||.   :|..  |.:|.||:  .|.|....|.|:|.:..  .
  Fly   398 ALSIHLVAIFIGLIFVQCDVGAIAGV---EGGK--LKQPYCSS--QCLCTPTAFMPVCPENSSVT 455

  Fly   622 YISACHAGCSSSSLRPSDNRTLYSDCACIPDAP-------EAVNGYC-DNNCKNFIYFILIFAIC 678
            |.|.|:|||:..:  ..::..|:..|:|..|..       .|..|.| .:||::.|....|.:|.
  Fly   456 YFSPCYAGCTKKT--TINSFQLFEGCSCSGDQSLNSTGQMRATAGACSSDNCQSAIIIFQIMSIS 518

  Fly   679 V-FMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWKSVCGK 742
            | |:.....:|..|:.:|...|:||::|:......:|||..||..:.|..|..:.|:.|   ...
  Fly   519 VAFLMGVGAIGKTLITLRAVLPQDKSLALAFELMIVGLFAYVPVHLSYDIVTRTTCVYW---APN 580

  Fly   743 HGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWRKAHRIDI---------------------- 785
            :..|.|.:..........:||.::..:.|.|::|:..|..:::
  Fly   581 YERCLLRETPKHGNILDILTASLILASVLFDILVYIFAKGLNLYNCKVTDNNYTPSLYAPIPHED 645

  Fly   786 ---APEDPQEGGPASNGRTLEVSESKQPITPAPDT 817
               :|..|:.|.|.:...|....: ::...|.|.|
  Fly   646 ATTSPSAPRGGSPVTTTTTSSPIQ-RRDAAPEPRT 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	153/619 (25%)
Oatp33Eb	NP_609570.1	oat	23..619	CDD:273279	165/671 (25%)
		MFS	50..>267	CDD:119392	62/272 (23%)
		KAZAL_SLC21	430..483	CDD:238650	17/56 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446203
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840