Protein Alignment Oatp74D and Slco1a6

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001368859.1
• Gene: Slco1a6 / 28254
• MGIID: 1351906
• Length: 670
• Species: Mus musculus
• Alignment Length: 677
• Identity: 188/677 - (27%)
• Similarity: 321/677 - (47%)
• Gaps: 83/677 - (12%)

  Fly   168 RRFASTHVFMVVFLLAY---ILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAML 229
            |.||...||::..:.||   ||.|:||:   :::|.:|:.|.|.:...|::..:.|||.:...:.
Mouse    14 RCFAKIKVFLLALIWAYISKILSGVYMS---TMLTQLERQFNISTSIVGLINGSFEMGNLLVIVF 75

  Fly   230 LTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNA 294
            ::||..:.|||..|..|..:..:..|..:||||:.|.       ...:|.:||.:|..|
Mouse    76 VSYFGTKLHRPIMIGVGCAVMGLGCFIISLPHFLMGR-------YEYETTISPTSNLSS------ 127

  Fly   295 SSEQVNPNLCILGGNQ----THSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVAT 355
                 |..||:...:|    |...:||.:|.:         :::.:.:..|::: .|||:|.:..
Mouse   128 -----NSFLCVENRSQTLKPTQDPAECVKEIK---------SLMWIYVLVGNII-RGIGETPIMP 177

  Fly   356 LGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFSNPGFD-----ATDPRWI 415
            |||.||:|...|:.||:|:.:....:::||..|::.|.||...||:..:...|     .||.||:
Mouse   178 LGISYIEDFAKSENSPLYIGILEVGKMIGPILGYLMGPFCANIYVDTGSVNTDDLTITPTDTRWV 242

  Fly   416 GAWWLGPVAIGSLMLLASIAMFSFPKQL--RGKQKPPGQTATPAAPVEPEEKPK------LKDFP 472
            ||||:|.:....:.:|.||..|.|||.|  .|.| ..|.....|...:..:|.|      :|:|.
Mouse   243 GAWWIGFLVCAGVNVLTSIPFFFFPKTLPKEGLQ-DNGDGTENAKEEKHRDKAKEENQGIIKEFF 306

  Fly   473 KTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIV 537
            ..::....|.|.|....:.|..:..:|.:..:.|||||..|.::|..|..:........:..|.:
Mouse   307 LMMKNLFCNPIYMLCVLTSVLQVNGVANIVIYKPKYLEHHFGISTAKAVFLIGLYTTPSVSAGYL 371

  Fly   538 ISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMF-IGCSMNDFAGYKPS--------DGNSPA 593
            ||| ||:|:.......||.||....:....:.:..| :.|.....||...|        |..:..
Mouse   372 ISG-FIMKKLKITLKKAAIIALCLFMSECLLSLCNFMLTCDTTPIAGLTTSYEGIQQSFDMENKF 435

  Fly   594 LIEPTCSAALNCTCDKENFAPICA-DGKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDA--PE 655
            |.:  |:.  .|.|..:.:.|:|. :|..|:|.|.|||..|.  .:....::.:|:||..:  ..
Mouse   436 LSD--CNT--RCNCLTKTWDPVCGNNGLAYMSPCLAGCEKSV--GTGANMVFQNCSCIRSSGNSS 494

  Fly   656 AVNGYCDN--NCKNFI-YFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFG 717
            ||.|.|..  :|.|.: ||::|...|.|.:|.:.:...::.:||...::|::.:|:....:.||.
Mouse   495 AVLGLCKKGPDCANKLQYFLIITVFCCFFYSLATIPGYMVFLRCMKSEEKSLGIGLQAFFMRLFA 559

  Fly   718 NVPCPIIYGAVVDSACLIWKSV-CGKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWRKAH 781
            .:|.||.:||::|..||.|.:: ||:.|||..|:..:||:.:||:.|.:.....|....:.|...
Mouse   560 GIPAPIYFGALIDRTCLHWGTLKCGEPGACRTYEVSSFRRLYLGLPAALRGSIILPSFFILRLIR 624

  Fly   782 RIDIAPEDPQEGGPASNGRTLEVSESK 808
            ::.| |.|       ::...:|::|:|
Mouse   625 KLQI-PGD-------TDSSEIELAETK 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	172/614 (28%)
Slco1a6	NP_001368859.1	oat	1..625	CDD:273279	182/649 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	633..670		3/11 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820