Protein Alignment Oatp74D and F21G4.1

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_509659.3
• Gene: F21G4.1 / 181203
• WormBaseID: WBGene00009023
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 685
• Identity: 176/685 - (25%)
• Similarity: 292/685 - (42%)
• Gaps: 107/685 - (15%)

  Fly   172 STHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGR 236
            |.::|:::.:|...:||.|:.|.|.::||:||.|...|:.:|.|||..::|.....:|:.|....
 Worm    15 SINIFVLLMVLVIAVQGTYLGYVVGMLTTLEKRFGFSSEKSGWLLSLYDIGHTMAILLIGYIGSH 79

  Fly   237 GHRPRWIACGMVLFSIAAFSCALPHFIFG------EQLMHSSVILQQTQVSPPNNSFSSHWLNAS 295
            .|.||....|::|.|::.|..|||...:|      ||||...                    .|.
 Worm    80 YHLPRITGIGVILSSLSMFMLALPVLFYGTADYTQEQLMQKK--------------------EAY 124

  Fly   296 SEQVNPNLCILGGNQ--THSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGI 358
            |.:::   |...|.:  :..|.:|..|       |.:.|...:.:.||.|. :||......|:..
 Worm   125 SVEMS---CDTNGRREISSQGEDCWRE-------HHEHTNAFIILAFGQLF-AGIFAAPFNTIAY 178

  Fly   359 PYIDDNVGSK-QSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFSN-PGFDAT-DPRWIGAWWL 420
            .|||.||..| :||..:.:...|...|||.||:..|.....|.:..: |....| |..|||||||
 Worm   179 VYIDSNVKQKRESPFLLGLLTSMYAFGPALGFMLSSILNGVYTSLGDAPDHIGTHDEHWIGAWWL 243

  Fly   421 GPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAPVEPEEKPK------------LKDFPK 473
            |.:..||..|:.::..|.||:    ..|.|...........|:..|:            |::||.
 Worm   244 GFLVCGSAYLILAVPFFFFPR----TYKHPDSFHLMLEHSRPQVSPEDRLTFKENITLFLREFPM 304

  Fly   474 TVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGI---- 534
            .:::.::|.:.:....:.:|....|.|..|:|||::|||:..:   |:|...:.||:.:|.
 Worm   305 VLKKLITNKVYITMVIAWMFGSYLIGGYQTYLPKFIETQYGRS---ASMADIYSGIISVGAIAVS 366

  Fly   535 ----GIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMN--------DFAG---- 583
                |.::|...|..|......:.:||     |.....||.|.:|||..        |:|.
 Worm   367 TALGGWILSRYNIAPRSSIICLIGSWI-----VILVSYIIGMNLGCSQPKVEGLTYVDYASRWHF 426

  Fly   584 YKPSDGNSPALIEPTCSAALNCTCDKENFAPICADGKMYISACHAGCSSSSLRPSDNRTLYSDCA 648
            |...:.....|....|...|       .|..:..:|:.:.|.|||||:...:..:    .:|:|.
 Worm   427 YHHREREQECLEYCNCETVL-------KFDGVSYNGQNFYSPCHAGCTEYDIYSN----TWSNCQ 480

  Fly   649 C----IPDAPEAVNGYCDNNCKNFIYFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVI 709
            |    :.|     .|....:|..|..::.:..|.:|:.:...:.:|::|:|....::|.:|:.:.
 Worm   481 CAYGNMVD-----KGLVHPDCGIFFAYLAVMLIGLFIGNLFFMVTMMIVLRSVFDEEKVIALSLA 540

  Fly   710 QSAIGLFGNVPCPIIYGAVVDSACLIWKSVC-GKHGACSLYDADTFRQYFLGITAGIMFLAFLMD 773
            .....|||.:|.|:|||..:|..|::|...| .:.|.|.|||.|.|.:.|.|:.:.....|.:..
 Worm   541 SFITNLFGFIPAPVIYGFFIDLCCILWNRQCPNERGNCVLYDNDMFTKMFHGVNSFFQVFAIIFA 605

  Fly   774 LVVWRKAHRIDIAPEDPQEGGPASNGRTLEVSESK 808
            .:.:..:..:.:..|.|....|.|..|.....|.:
 Worm   606 GICYWLSKTVKLPEEMPMVDFPESREREYRDEEEE 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	165/626 (26%)
F21G4.1	NP_509659.3	OATP	18..586	CDD:281175	165/626 (26%)
		MFS	20..>402	CDD:119392	113/424 (27%)
		KAZAL_SLC21	433..481	CDD:238650	13/58 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28658
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830