Protein Alignment Oatp74D and K02G10.5

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001294796.1
• Gene: K02G10.5 / 180742
• WormBaseID: WBGene00019346
• Length: 642
• Species: Caenorhabditis elegans
• Alignment Length: 735
• Identity: 189/735 - (25%)
• Similarity: 310/735 - (42%)
• Gaps: 146/735 - (19%)

  Fly   135 ESEESDFDSDLNGGSSAESSSSCGLFGCRPR---WARRFASTHVFMVVFLLAYILQGMYMTYFVS 196
            |::|:.|                |....||:   |...|..   ||.:.....:|||..:...||
 Worm     3 EADETPF----------------GFSWFRPKGLQWLSNFIP---FMSILSANAMLQGAIVNGLVS 48

  Fly   197 V-ITTIEKLFQIKSKTTGILLSASEMGQICTAML--LTYFAGRGHRPRWIACGMVLFSIAAFSCA 258
            | |::|||.|::.|..:||..:..::  ..|.||  |..:|.:.::.:.|..||::..|.:....
 Worm    49 VSISSIEKRFKLTSTQSGIFAATYDV--FVTVMLIPLALYATKVNKVKCIGLGMMIVGIGSILVI 111

  Fly   259 LPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQL 323
            :|.:..|..                           |..:|..::|:.||    ....|:|....
 Worm   112 IPEYTAGPY---------------------------SVGEVKKDVCVTGG----PDKVCSEGSSD 145

  Fly   324 EQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASG 388
            ..::|.::.:::|...|     .|||.:.:.|.||..:|:....|::...:|:.:....:|||..
 Worm   146 TFSAHRELLLLLLSQAF-----VGIGASPLFTYGITCLDEFDSHKRTGRNLALYMIASTVGPALA 205

  Fly   389 FIFGSFCTR----WYVNFSNPGFD-ATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQK 448
            |:...|..|    |..:.:..|.| :.|||:||.||:|.|..|.:.|..:..:..|||:|:
 Worm   206 FVGCGFMLRLWGDWRTSPAEMGIDNSADPRFIGMWWIGFVVCGFVALFTAFPLIMFPKRLK---- 266

  Fly   449 PPGQTATPAAPVEPEEKPKLKDFPKTVRRQLSNDILMFRTASCVFHLLP-------IAGLYTFLP 506
              ..|...|..|...:....|||............::|:..:|:..:|.       :.|..||:|
 Worm   267 --DTTVRKANDVHRTDASLDKDFSDHKYEFFKIIFMLFKNKTCMCVILMQTIEAMLMNGYITFIP 329

  Fly   507 KYLETQFRLATYDANMIAAFCGILVMGIGIV-------ISGLFILKRKPTARGVAAWIAFTALVY 564
            |.|||....::.:|::|.   |.:|:.:|||       ||.||..:.||:...|   |.|.  :.
 Worm   330 KLLETLLGFSSGNASLIT---GGVVVPVGIVASYIGGRISKLFENRFKPSMYFV---IVFG--IM 386

  Fly   565 SAGMIILMFIGC-SMNDFAGYKPSDGNSPALIEPTCSAALNCTCDKENFAPICA-DGKM-YISAC 626
            :||....:.|.| |:|.:....||..........|||.  ||.|| ..|.|:|: |.|: ::|.|
 Worm   387 AAGCSSCLLIRCESLNVYGVNVPSSDLPRYGALETCSE--NCHCD-SFFNPVCSEDSKLTFLSPC 448

  Fly   627 HAGCSSSSLRP-----SDNRTLYSDCACIPDAPEAVNGYCDNNCKNFIY-FILIF---AICVFMH 682
            ||||:.   .|     :.|   :::|.|..:. ....||||.:|:..|| ||::|   :.|:|:.
 Worm   449 HAGCAD---MPGIKFGASN---WTNCGCSKNT-IVKKGYCDASCQKQIYQFIIMFIALSFCIFIT 506

  Fly   683 STSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWKSVCGKHGACS 747
            :.....|.|.|:...| :|.....|.:...|  .|::|..|::|.::|..|:.|:..|... .|.
 Worm   507 APVLQSSSLRVVNHKH-RDHFTCFGWLWMRI--LGSIPGAIVFGYIIDVNCMYWQKDCVSQ-KCQ 567

  Fly   748 LYDADTFRQYFLGITAGIMFLAFLMDLVVWRKAHRIDIAPEDPQEGGPASNG----RTLEVSESK 808
            .|:|......|...|..:.|...::          :.:|....|| ...|||    ||||...|:
 Worm   568 FYNASNLGWAFFYFTIAVKFTGGIL----------LFLAAYCYQE-SDKSNGKESCRTLETDTSE 621

  Fly   809 Q---------PITPAPDTTV 819
            .         |...:|:|.|
 Worm   622 SVKMSYEKNLPSGLSPETMV 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	163/612 (27%)
K02G10.5	NP_001294796.1	oat	1..602	CDD:273279	175/693 (25%)
		MFS	36..>390	CDD:119392	102/405 (25%)
		KAZAL_SLC21	421..470	CDD:238650	21/57 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810