Protein Alignment Oatp74D and LOC1277224

DIOPT Version :10

• Sequence 1: NP_648989.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_316669.4
• Gene: LOC1277224 / 1277224
• VectorBaseID: AGAMI1_000322
• Length: 772
• Species: Anopheles gambiae
• Alignment Length: 767
• Identity: 224/767 - (29%)
• Similarity: 361/767 - (47%)
• Gaps: 94/767 - (12%)

  Fly    92 KNGLGN-ILSSNNNGTGNGHSLSEKYAHEQ-------APLTGGYKLPPRSSESEE---------S 139
            :.|.|| ::.....||..... .::..|:|       ....|.|.:.....::|:         .
Mosquito    16 QTGSGNGVVGEGREGTDRAED-DDRTGHDQVTEQVTVGERKGSYAVYNNGKKAEKVPEMEKMLPE 79

  Fly   140 DFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVF-LLAYILQGMYMTYFVSVITTIEK 203
            |.: |:.........:|||.:..:....:|||:..|::.:: ::..|....| .||...|||:||
Mosquito    80 DVE-DMYRDMPVTKDTSCGFWMFQGPMLQRFANKKVYVFMYGVVGCIFSATY-AYFNGTITTLEK 142

  Fly   204 LFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQL 268
            .::|.||.|||:...:::..:..:.:|:|:||:||||||||.|:::.:...:..||||.::|...
Mosquito   143 RYKIPSKNTGIISVGNDISALLLSAILSYYAGKGHRPRWIAFGLLMITAFCWLTALPHLLYGPGE 207

  Fly   269 MHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITV 333
            ...|:..:.......|.  ::..:.|...::   ||.....:   |:||..|..         |:
Mosquito   208 AALSLTTEYGATYDANQ--TAEVMEAQKAKI---LCRTNATR---GAECEREEG---------TL 255

  Fly   334 IVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRW 398
            ....:.|.:...||||.:...|||:.|:|||:...::|..::|:..:|:||||.|:...|:..:.
Mosquito   256 APQIVLFIAQFISGIGSSLYYTLGVSYMDDNIKKSKTPALVSVSYFLRMLGPAIGYTLASYFLKL 320

  Fly   399 YVNFS-NPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQL---------RGKQKPPGQT 453
            |::.| .|....|||||:||||:|.:.:|:::...:|.|..|||||         ..:::..|..
Mosquito   321 YISPSMTPTISNTDPRWLGAWWMGWLILGAVLAFFAIFMAMFPKQLPRAAARKRIAQEKRRLGMQ 385

  Fly   454 ATPAAPVEPEEKPKLKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATY 518
            .:.|:..|.|.....||..||.:|.|.|.|||....:.||:.......:.|.|||:|||::.:..
Mosquito   386 LSDASKREDELPASFKDMLKTFKRLLRNKILMLNNIASVFYFFGYMPYWIFTPKYIETQYKQSAS 450

  Fly   519 DANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSM--NDF 581
            .::::.....:....||:::|||.|.|.||.||.:|||.....|:...|||...|:|||.  |..
Mosquito   451 TSSLVTGTVALCFSAIGVLLSGLVISKFKPRARYMAAWNVIVGLLSVMGMIAYAFLGCSASENSV 515

  Fly   582 AGYKPSDGNSPALIEPTCSAALNCTCDKENFAPICA-DGKMYISACHAGCSSSSLRPSDNRTLYS 645
            ....||..:    :.|||::|  |.||...::|||. ||..|||||||||...:  ...:..:|.
Mosquito   516 IVNIPSQTD----LTPTCNSA--CQCDYVKYSPICGEDGNTYISACHAGCKRQN--QYGDLKIYG 572

  Fly   646 DCACIP-----DAP-----------------------------EAVNGYCDNNC-KNFIYFILIF 675
            :|:||.     .:|                             .|:.|.|..|| |.||.|:::.
Mosquito   573 ECSCITPVVNYTSPLYNQLLTGGNHTTTSTAAARDENMFSLGGSAIAGPCPLNCQKEFITFLVVM 637

  Fly   676 AICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWKSVC 740
            ....|..:|....:.|:.:||...||||::||.....:.|...:|.||.:|.|:|..||:|...|
Mosquito   638 CFLKFSGATGRASNFLVSVRCVDEKDKAVSMGFGMMVLSLMSFIPSPIFFGLVLDKTCLVWGKTC 702

  Fly   741 GKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWRKAHRIDIAPEDPQE 792
            ...|.|.|||.:|.|.....|.|..:.:..|.|..||.....:.|..::.|:
Mosquito   703 TGKGNCWLYDGETLRYLLNFIAAAFVLVGTLFDCGVWYYVKDLKIFDDEVQD 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_648989.1	OATP	175..754	CDD:460821	196/627 (31%)
LOC1277224	XP_316669.4	OATP	114..716	CDD:460821	196/627 (31%)