Protein Alignment Oatp74D and slco1e1

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_009299376.1
• Gene: slco1e1 / 100332946
• ZFINID: ZDB-GENE-100818-2
• Length: 695
• Species: Danio rerio
• Alignment Length: 677
• Identity: 179/677 - (26%)
• Similarity: 303/677 - (44%)
• Gaps: 104/677 - (15%)

  Fly   162 CRPRWAR--RFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQI 224
            |.|....  |.:|..:|:.....||..:.:..||..|.||.||:.|.:.|...|::..:.|||.:
Zfish    19 CSPEAPEEPRCSSLKIFIGALSFAYFSKTLCGTYMKSAITQIERRFDLSSSAVGLVDGSFEMGNL 83

  Fly   225 CTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSV--ILQQTQVSPPNNSF 287
            ....::::|..|.||||.|..|..|.:|.:....|||...|.....:::  ...:|.|..|
Zfish    84 LFVAVVSHFGARLHRPRLIGMGCFLMAIGSALTGLPHVFMGRYKFDTAIQGFANETVVIAP---- 144

  Fly   288 SSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTA 352
                   .....||:...:......:|::|.::      ..|.:.:.|   |.|:.| .|||:|.
Zfish   145 -------CQYPTNPSEHSIQHIDNTTGTDCVKD------PGSSMWIYV---FLGNAL-RGIGETP 192

  Fly   353 VATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFSNPGFDAT-----DP 412
            |..|||.||||...::.|..|::....:.:|||..||:.||.|.:.||:......|:.     |.
Zfish   193 VTPLGISYIDDFAKAENSAFYISCLQTIMLLGPMFGFLLGSMCAKLYVDIGFVSVDSVSITPQDA 257

  Fly   413 RWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAPVEPEEKPKL--------- 468
            ||:||||||.....:.::|:.:..:..|:.|               |.:.||:.::
Zfish   258 RWVGAWWLGFFVSSAFLVLSGVPFWFLPRSL---------------PKQGEEEKEICNTDDANKE 307

  Fly   469 ----------------KDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLAT 517
                            |.|..:::|.|............|.......||.||..||:|.||..:.
Zfish   308 HSVLQTTHTMTLADIAKGFLPSLKRLLCTPAYFLLLCGIVLKFNSFIGLLTFKAKYMEQQFGQSA 372

  Fly   518 YDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIG--CSMND 580
            ..||.:.....:.|:.:||.:.|| ::||...:....|.::|.. .::|.:::|:..|  |....
Zfish   373 SRANFLIGVLILPVVAVGIFLGGL-LMKRYKLSVVAGAQLSFIT-SFTAFLLLLLHFGTKCDNVP 435

  Fly   581 FAG---------YKPSDGNSPALIEPTCSAALNCTCDKENFAPICAD-GKMYISACHAGCSSSSL 635
            .||         |.|||..|   :|..|:.  :|:|....:.|:|:| |..|:|.|.|||::|:
Zfish   436 VAGLTVSYNGTPYMPSDQRS---LESQCNQ--DCSCSTSEWDPVCSDSGITYMSPCLAGCTAST- 494

  Fly   636 RPSDNRTLYSDCACI--PDAPEAVN----GYCDNN---CKNFIYFILIFAICVFMHSTSEVGSML 691
             .....|::.:|:|:  |...|...    |.|...   .::|..::.:..:..|::|.......:
Zfish   495 -GQGKNTVFHNCSCVLSPSPAEGGRSVSLGQCPQGSACARSFTSYMAVSVLSSFINSLGTTPGYM 558

  Fly   692 LVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIW-KSVCGKHGACSLYDADTFR 755
            :::||..|:.|::|:|:....:...|.:|.||.:||::|||||.| ...||..|||.:||::.:|
Zfish   559 IIIRCIAPELKSLALGIQTLVMRTLGGIPAPIYFGALIDSACLKWGLKKCGGRGACRIYDSNMYR 623

  Fly   756 QYFLGIT---AGIMFLAFLMDLVVWRK 779
            ..||.:|   :|..:...:..:|:.|:
Zfish   624 VIFLSLTTALSGCSYFFIIAVIVLLRR 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	168/632 (27%)
slco1e1	XP_009299376.1	OATP	34..622	CDD:281175	168/632 (27%)
		MFS	36..>288	CDD:119392	77/272 (28%)
		KAZAL_SLC21	456..508	CDD:238650	17/55 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920