Protein Alignment Oatp74D and slco1f2

DIOPT Version :10

• Sequence 1: NP_648989.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001121745.3
• Gene: slco1f2 / 100190901
• ZFINID: ZDB-GENE-080305-3
• Length: 662
• Species: Danio rerio
• Alignment Length: 686
• Identity: 204/686 - (29%)
• Similarity: 319/686 - (46%)
• Gaps: 72/686 - (10%)

  Fly   143 SDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQI 207
            ||.|   ...|.:.|    |.||       ..:|:......|..:.|..:|..|.||.||:.|:|
Zfish    11 SDRN---QKTSQTKC----CPPR-------LKIFIAALAFCYFSKSMTASYTKSTITQIERRFEI 61

  Fly   208 KSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSS 272
            .|.|.||:....|||.:....|::|...:.|||:.|..|::|..|.....|.||||.|.
Zfish    62 PSSTVGIIDGGFEMGNMLVITLVSYIGAKFHRPKIIGAGVLLMGIGTLLMASPHFIMGR------ 120

  Fly   273 VILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLC 337
             ....|..:..|::.:...::..|......|     .|.:||  |.:    |:|..|.:.|||:
Zfish   121 -YKYGTAATHTNDAGNFTVISTCSSDSQKTL-----QQPYSG--CRK----EEAESSPLWVIVV- 172

  Fly   338 IFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWY--- 399
              .|:.: .|||:.::..||:.::||....:.|..|:.....::.:||..||:.||.|...|
Zfish   173 --LGNTM-LGIGEASIIPLGMSFVDDYARPENSAFYIGCLNTIKGIGPIFGFVLGSLCANLYVDI 234

  Fly   400 --VNFSNPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQTATPAAPV-E 461
              ||..:......|.||:||||||.|..|.|.|||:...:..||.|....:......||...: .
Zfish   235 GLVNKESVTITPQDSRWVGAWWLGYVVSGLLTLLAAFPFWFLPKALPENSQISLLDNTPQQHITT 299

  Fly   462 PEEKPKLKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAF 526
            |.....:|||..|.:|.|:|.|.:...|..:......|.|.|:.|||||.||..:...||.:...
Zfish   300 PSLTEIVKDFAPTFKRLLTNKIYILYLAYSIVAFNDFAILVTYTPKYLEQQFGQSASKANFLIGV 364

  Fly   527 CGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMF-IGCSMNDFAGYK-PSDG 589
            ..:..:.:|:.:||| ::||.......:|.:....:|.:..:.:..| :.|...|.||.. |..|
Zfish   365 TCVPAVALGVFLSGL-MMKRFKWGLLASARVNLLNIVATVFLTVPFFALSCENLDIAGVTVPYQG 428

  Fly   590 NSPAL-----IEPTCSAALNCTCDKENFAPICAD-GKMYISACHAGCSSSSLRPSDNRTLYSDCA 648
            ::...     :.|.|:|  :|.|...::.|:|.: |..|||.|||||||:  :.:.....:.||.
Zfish   429 STEVQGVTSDVLPPCNA--DCGCPDLHWDPVCGENGVTYISPCHAGCSST--QGAGRNMTFHDCR 489

  Fly   649 CIPD------APEAVNGYCDN--NCKNFIYFIL-IFAICVFMHSTSEVGSMLLVMRCTHPKDKAM 704
            ||..      ...||.|.|..  ||...:|..| :.::.:|::|...|....:.:|...|:.|::
Zfish   490 CIQSWGLSVGNSSAVLGQCSQNPNCNRMMYLYLGLQSLALFVYSLGAVPLFTMSLRIVDPELKSL 554

  Fly   705 AMGVIQSAIGLFGNVPCPIIYGAVVDSACLIW--KSVCGKHGACSLYDADTFRQYFLGITAGIMF 767
            ::||:..:|.:.|.:|.||.:||:|||:||.|  :..||: |||.:||.:|||..|.|:|..:..
Zfish   555 SVGVLLLSIRVLGGIPAPIYFGALVDSSCLKWGQRKSCGR-GACRIYDIETFRFLFQGLTNCLRV 618

  Fly   768 LA--FLMDLVVWRK---AHRIDIAPEDPQEGGPASN 798
            ||  .|....:|.|   .:...|:.:...:.||:.:
Zfish   619 LACSLLWIATIWIKRKMQNDKQISKDMEMQRGPSDD 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_648989.1	OATP	175..754	CDD:460821	182/603 (30%)
slco1f2	NP_001121745.3	None