Protein Alignment Oatp74D and slco1f3

DIOPT Version :9

• Sequence 1: NP_001163460.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001129156.2
• Gene: slco1f3 / 100190900
• ZFINID: ZDB-GENE-080212-5
• Length: 588
• Species: Danio rerio
• Alignment Length: 632
• Identity: 187/632 - (29%)
• Similarity: 293/632 - (46%)
• Gaps: 93/632 - (14%)

  Fly   221 MGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNN 285
            ||.|....|::|...:.|||:.|..|::|..|.....|.||||.|.       ....|..:..|:
Zfish     1 MGNILVITLVSYVGAKFHRPKIIGAGVLLMGIGTLLMASPHFIMGR-------YRYGTAATHTND 58

  Fly   286 SFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQ 350
            ..:...::..|......|     .:..||  |    |.|::..|.:.|:||   .|:.: .|||:
Zfish    59 DGNFTVISTCSSDSQETL-----QKPFSG--C----QKEESGRSPLWVMVL---LGNTM-RGIGE 108

  Fly   351 TAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFSNPGFDAT----- 410
            .::..||:.:|||....:.|..|:.....:.::||..||:.||.|...||:..:. :.|:
Zfish   109 ASIVPLGMSFIDDYARPENSAFYIGCLNTLGVIGPIFGFMLGSLCANLYVDIDSV-YQASVTITP 172

  Fly   411 -DPRWIGAWWLGPVAIGSLMLLASIAMFSFPK------QLRGKQKPPGQTATPAAPVEPEEKPKL 468
             |.||:||||||.|..|...|||:..::.||:      |:.....|..|..|     .|.....:
Zfish   173 QDYRWVGAWWLGYVVSGLFTLLAAFPLWFFPRALPENSQISELNHPRQQHKT-----TPSLTEIV 232

  Fly   469 KDFPKTVRRQLSNDILMFRTASCV--FHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILV 531
            ||||.:.:..|:|.|.:...|..:  |:...|...||  |||||.||..:....|.:.....:..
Zfish   233 KDFPPSFKHLLTNKIYILYLAHSIVAFNDFAIGASYT--PKYLEQQFGQSASKTNFLIGATSVPA 295

  Fly   532 MGIGIVISGLFILKRK----PTAR-----GVAAWIAFTALVYSAGMIILMFIGCSMNDFAGYK-P 586
            :.:||.:|||.:.:.|    .:||     |||  :.|.|:.:.|       :.|...:.||.. |
Zfish   296 VALGIFLSGLMMKRFKWDLLTSARVNLYAGVA--MLFLAVPFFA-------LSCGNLEVAGVTVP 351

  Fly   587 SDGNSPAL-----IEPTCSAALNCTCDKENFAPICAD-GKMYISACHAGCSSSSLRPSDNRTLYS 645
            ..|::...     :.|:|:|  :|.|...::.|:|.: |..|||.||||| :|:|....|.| :.
Zfish   352 YQGSTEVQGVISDVLPSCNA--DCGCPDIHWDPVCGENGVTYISPCHAGC-NSTLGAGRNMT-FH 412

  Fly   646 DCACIPD------APEAVNGYC--DNNCKNFIYFIL-IFAICVFMHSTSEVGSMLLVMRCTHPKD 701
            ||.||..      ...||.|.|  |..|....|..| :.::..|::|...|....|.:|...|:.
Zfish   413 DCGCIQSWGLSVGNSSAVLGQCSRDPKCNRMFYIYLGLQSLAFFVYSLGTVPYFTLSLRIVDPEL 477

  Fly   702 KAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIW---KSVCGKHGACSLYDADTFRQYFLGITA 763
            |::::|::...:.:.|.:|.||.:|:::||.||.|   || ||: |||.:||.:|||..|.|:|.
Zfish   478 KSISVGMLLFTVRVLGGIPAPIYFGSLIDSTCLKWGRTKS-CGR-GACRIYDIETFRFLFQGLTI 540

  Fly   764 GIMFLAFLMDLVVWRKAHRIDIAPEDPQEGGPASNGRTLEVSESKQP 810
            |:..||:.:   :|.....|....::.::   .|....|:.|.|..|
Zfish   541 GLRVLAYSL---LWIATIEIQRKMKNDKQ---LSRDTELQKSPSNDP 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp74D	NP_001163460.1	OATP	175..754	CDD:335235	171/574 (30%)
slco1f3	NP_001129156.2	OATP	1..531	CDD:281175	171/574 (30%)
		MFS	<88..>339	CDD:119392	80/271 (30%)
		KAZAL_SLC21	366..418	CDD:238650	23/55 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D434101at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920