Protein Alignment SecCl and glra4a

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_005169655.1
• Gene: glra4a / 83413
• ZFINID: ZDB-GENE-010410-3
• Length: 457
• Species: Danio rerio
• Alignment Length: 517
• Identity: 144/517 - (27%)
• Similarity: 236/517 - (45%)
• Gaps: 93/517 - (17%)

  Fly    12 ITLILVLSI------WTSVGVKAEEEECPSMADAGSLQQTQLIQRLT-HVCRYDRLERPFEYDSD 69
            |.::.|||.      :..:|...||.:..|......:..:..:.:|. ....||...||     :
Zfish     6 IRILYVLSFFFFQGGFIRLGSCKEEIKSSSRPAQKPMSPSDFLDKLMGRTSGYDARIRP-----N 65

  Fly    70 GKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERLWL 134
            .|..|:.|...|::....::....:.::::..|:.::.|.||||..:..:...|....| :.:|.
Zfish    66 FKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYSEYPDASLDLDPSML-DSIWK 129

  Fly   135 PHIFFANERESSI--LGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLES 197
            |.:|||||:.::.  :.||.|  |..:...|||:.|.|:...|.|.|:.:.||.|.|.|:..|||
Zfish   130 PDLFFANEKGANFHEVTTDNK--LLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLES 192

  Fly   198 WMYNTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSD-GDNLRHGAFAGNYSSLSFTV 261
            :.|..:|||.||....|:....::.|.::.:.:        :.| |...:| ...|.::.:....
Zfish   193 FGYTMNDLIFEWLSDNPVQVADDLTLPQFVLKE--------EKDLGYCTKH-YNTGKFTCIEVKF 248

  Fly   262 NLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSY 326
            :|:|::|:||:..|:||::||.:||||||:..||:|.|:.||.:|:|:..|.||....:||||||
Zfish   249 HLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSY 313

  Fly   327 IKVSEVWFLGCTFFIFGSLVEFAFVNTIWRR-KENIELKKVNSKYIIKSTLTPRPARRQIGGSLS 390
            :|..::|...|..|:|.:|:|:|.||.:.|: ||.|.|:|             :..|::|...|.
Zfish   314 VKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRK-------------KQRRQRIEEELV 365

  Fly   391 NESRA--------RSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSI 447
            .|||.        ..|            ::..:||..:|.:.:.   |..|:......||.....
Zfish   366 RESRGFYFRGYGLGHC------------LQTKDGTAVEGSSVFA---PPPPVQVLYDGEAVRKRF 415

  Fly   448 CSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVYVL 509
                        ||:.|:                 ||..||.:||..||.||..||....||
Zfish   416 ------------VDRAKR-----------------IDTISRAVFPLSFLIFNVFYWITYKVL 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	134/474 (28%)
		Neur_chan_LBD	44..267	CDD:280998	58/226 (26%)
		Neur_chan_memb	275..503	CDD:280999	71/236 (30%)
glra4a	XP_005169655.1	LIC	27..445	CDD:273305	137/491 (28%)
		Neur_chan_LBD	48..254	CDD:280998	58/222 (26%)
		Neur_chan_memb	261..442	CDD:280999	71/237 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910