Protein Alignment SecCl and glrba

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_571856.1
• Gene: glrba / 83412
• ZFINID: ZDB-GENE-010410-2
• Length: 498
• Species: Danio rerio
• Alignment Length: 552
• Identity: 141/552 - (25%)
• Similarity: 249/552 - (45%)
• Gaps: 122/552 - (22%)

  Fly    14 LILVLSIWTSV--------GVKAEEEECPSMADAGSLQQ------TQLIQRLTHVCRYDRLERPF 64
            ::|:|.:..|.        |.|.::..|||...|..|.:      :.::.||  :..||...||
Zfish    12 ILLMLLVQFSAEEGGKPKKGKKGKQVICPSQLSAEDLDRVPANSTSNILNRL--LMTYDSRIRP- 73

  Fly    65 EYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLS 129
                :.|.:|:..|..|::....::....:.::::..|:.|:.|.||......:||.:.....:.
Zfish    74 ----NFKGIPVEDKVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLRLPTDFKSDALTVDPKMF 134

  Fly   130 ERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTV 194
            :.||.|.:|||||:.::.....::::|..:...|:|:||.|:..:|.|.:..|.||.|.|:|...
Zfish   135 QCLWKPDLFFANEKNANFHDVTQENILLFIFRNGDVLISMRLSVTLSCPLALQLFPMDTQYCKMQ 199

  Fly   195 LESWMYNTSDLILEWEPHTPISFDPEMRLTEY----------NMAQFWHNTTIVQSDGDNLRHGA 249
            |||:.|.|.||:..|:...|:..| |:.|.::          |..:|:..|
Zfish   200 LESFGYTTKDLVFMWQSGDPVQMD-EIALPQFDVKQEDIKYANCTKFYPGT-------------- 249

  Fly   250 FAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLS 314
              |.|:.:.....|:|::|||::..|.|:::||.:||:|||:..|||..|:.||..::||..:..
Zfish   250 --GYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGILSVLSLSSEC 312

  Fly   315 SSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPR 379
            :|.:..||||||:|..::|.:.|..:.|.||||:|.|..:....:.||.:|:            :
Zfish   313 TSLASELPKVSYVKAIDIWMIACLLYGFASLVEYAVVQVMLNSPKRIEAEKI------------K 365

  Fly   380 PARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVH-PNLPIIRTECAEAD 443
            .|.::......|::.|::.|:            ||.|..        .:| ..|.::...|.:
Zfish   366 MAEKEKAREKENKTPAKTNSA------------NGTGGT--------PIHVSTLQVVENRCKK-- 408

  Fly   444 TVSICSART---NND-----------------------HIVDVD------KDKKDTPPTFTTMTP 476
               :|::::   :||                       .:.|..      .:||..||  ..:.|
Zfish   409 ---VCTSKSDLRSNDFSIVGSLPRDFELSNFDCYGKPIEVTDASGKPQNKNNKKPAPP--KPVIP 468

  Fly   477 QEIAMWIDRRSRFLFPAMFLAFNALYWTFVYV 508
             ..|..:|..:|.|||..||.||.:||: ||:
Zfish   469 -SAAKRVDLYARALFPFTFLFFNVIYWS-VYL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	129/510 (25%)
		Neur_chan_LBD	44..267	CDD:280998	58/238 (24%)
		Neur_chan_memb	275..503	CDD:280999	66/260 (25%)
glrba	NP_571856.1	LIC	52..497	CDD:273305	129/509 (25%)
		Neur_chan_LBD	59..265	CDD:280998	58/229 (25%)
		Neur_chan_memb	272..494	CDD:280999	66/261 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910