Protein Alignment SecCl and gabra5

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_005166139.1
• Gene: gabra5 / 799124
• ZFINID: ZDB-GENE-081104-30
• Length: 453
• Species: Danio rerio
• Alignment Length: 509
• Identity: 123/509 - (24%)
• Similarity: 214/509 - (42%)
• Gaps: 106/509 - (20%)

  Fly    19 SIWTSVGVKAEEEECP---SMADAGSLQQTQLIQRLTHVCR--------YDRLERPFEYDSDGKR 72
            |:|  |||......|.   |.:..|:.::::|...:|...|        ||...||    ..|::
Zfish    13 SLW--VGVLFMTLTCHLSLSQSTTGTPKESELNDNITVFTRILDGLLDGYDNRLRP----GLGEK 71

  Fly    73 LPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKA---FNRSDNILGQKHLSERLWL 134
            : ..:||.|:|.....::...:::.:....:..::|:||.:|.   ....:|:     |:..:|.
Zfish    72 V-TEIKTNIFVTSFGPVSDTEMEYTIDVFFRQSWKDERLCFKGPMEMLPLNNL-----LASNIWT 130

  Fly   135 PHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWM 199
            |..||.|.::|........:.|..|..:|.::.:.|:..|..|.|..:.||.|...|.....|:.
Zfish   131 PDTFFLNGKKSIAHNMTTPNKLLRLKDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYA 195

  Fly   200 YNTSDLILEWE--PHTPISFDPE-MRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTV 261
            |..|:::.:|.  |...:....| .||.:|::......|..:.:.         .|.|:.:....
Zfish   196 YPISEVVYKWTKGPGKSVVVAEEGSRLNQYHLIGHTAGTEDISTS---------RGQYTVMMAHF 251

  Fly   262 NLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSY 326
            .|||:||::::..|:|..|.|.:|.|||||..::.|.|.:.|.:|:|:..|||.|...:||||:|
Zfish   252 YLKRKIGYFVIQTYMPCFMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAY 316

  Fly   327 IKVSEVWFLG-CTFFIFGSLVEFAFVNTI------WRRKENIELKKVNSKYIIKSTLTPRPARRQ 384
            ....: ||:. |..|:|.:|:|||.||..      |..|:.:|.::...|..:  .|:.:|
Zfish   317 ATAMD-WFIAVCYAFVFSALIEFATVNYFTKRSWAWDGKKALEAQQPKKKDPL--ALSKKP---- 374

  Fly   385 IGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICS 449
                                                  ||: |.:.|.....:..:.:.||.:.|
Zfish   375 --------------------------------------NNF-TANINKDAAISTISNSTTVQLKS 400

  Fly   450 ARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYW 503
            |..         |...|...|:.:::.      ||:.||.:||.:|..||.:||
Zfish   401 AEA---------KPAPDPKKTYNSVSK------IDKMSRIVFPVLFGTFNLVYW 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	115/482 (24%)
		Neur_chan_LBD	44..267	CDD:280998	50/236 (21%)
		Neur_chan_memb	275..503	CDD:280999	61/234 (26%)
gabra5	XP_005166139.1	Neur_chan_LBD	19..442	CDD:332142	118/501 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900