Protein Alignment SecCl and gabrz

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001108214.2
• Gene: gabrz / 561738
• ZFINID: ZDB-GENE-080303-26
• Length: 447
• Species: Danio rerio
• Alignment Length: 510
• Identity: 131/510 - (25%)
• Similarity: 231/510 - (45%)
• Gaps: 75/510 - (14%)

  Fly     4 LHL-SEIFWITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYD 67
            :|: |.:.::.|:|.:|......|...||..|           ..||:|  :..|::..|||..:
Zfish     1 MHVCSFVGFLLLLLFISRIMDGSVANTEEILP-----------PTIQKL--MKGYNKYLRPFFGN 52

  Fly    68 SDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERL 132
            .     |:.|...:.:..:..::...:.:.....|:.|:.|:||.:.. |:|.::.|:  |.|.|
Zfish    53 G-----PVTVGMSLDIASIDTISEINMDYTATIFLRQRWTDERLCFDG-NKSLSLDGR--LVELL 109

  Fly   133 WLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLES 197
            |:|..|..:.::|.:.....::.|..:.|.|.|:.:.|:..::.|.|:..|:|.|:|.|...|||
Zfish   110 WVPDTFIVDSKKSFLHDITVENRLIRIFPNGTVLYALRITTTVACSMDLTKYPMDRQTCMLQLES 174

  Fly   198 WMYNTSDLILEW-EPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTV 261
            |.||..|::..| ..:..:|....::|.:|.:..  |.|    |:.:.:..   .|||..|.|..
Zfish   175 WGYNVKDVVFYWTRGNQSVSGLDHLQLAQYTLED--HYT----SESEAVYE---TGNYPKLIFHF 230

  Fly   262 NLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVS- 325
            .|||.|.:::|:.|:||..:|.:||||||:...:.|.||.:|.:|:|:..||......:||..:
Zfish   231 KLKRSILYFILETYVPSSALVVLSWVSFWISQSSVPARICIGVTTVLTMTTLMMGARTSLPNANC 295

  Fly   326 YIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLS 390
            :||..:|:...|..||||:|:|:|..:.....:.|     ..:.|:....:..|  ..::.|.::
Zfish   296 FIKAIDVYLGICFSFIFGALIEYAVAHFCTLHQPN-----AANAYMYGQEMQER--EDEMNGIVT 353

  Fly   391 N-ESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIR-TEC-AEADTVSIC--SA 450
            : .|.|......:.::|...||.|...:.::.     .|..:.|..| |:| :.|..:..|  ..
Zfish   354 SFGSHALRARKREEMLSRMGSVNNPTPSESKE-----DVSSSQPQTRCTKCMSRARRIIRCLYCC 413

  Fly   451 RTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTF 505
            :..|.|                         :||..||..||..|:..|.||||:
Zfish   414 KVENPH-------------------------YIDNYSRLTFPLSFVIINLLYWTY 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	121/468 (26%)
gabrz	NP_001108214.2	LIC	26..444	CDD:455710	125/485 (26%)
		LGIC_ECD_GABAAR_pi	54..235	CDD:349805	50/192 (26%)
		Cys-loop	153..168	CDD:349805	6/14 (43%)