Protein Alignment SecCl and gabrg1

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_009305483.1
• Gene: gabrg1 / 556202
• ZFINID: ZDB-GENE-141215-66
• Length: 454
• Species: Danio rerio
• Alignment Length: 543
• Identity: 131/543 - (24%)
• Similarity: 221/543 - (40%)
• Gaps: 124/543 - (22%)

  Fly     1 MMNLH--LSEIFWITLILVLSIWTSVG-VKAEEEE------------CPSMADAGSLQQTQLIQR 50
            |::||  ..::.|: |..:|.:..:.| .|||||:            .|.:.::   ..|.::.:
Zfish     1 MVHLHPRRRKLVWL-LPGLLGVCMAFGPSKAEEEDYEDVPINKTWVLSPKVYES---DVTLILNK 61

  Fly    51 LTHVCRYDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAY-- 113
            |..  .||...||    ..|.| |.|::|.:||..:..::...:::.:.......:.|.||.:
Zfish    62 LLQ--GYDNKLRP----DIGVR-PTVIETAVYVNSIGPVDPINMEYTIDIFFAQTWYDSRLKFNS 119

  Fly   114 --KAFNRSDNILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLY 176
              |....:.|::|      ::|:|..||.|.|:|........:.|..|...|.|:.:.|:..:..
Zfish   120 SMKLLMLNSNMVG------KIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAE 178

  Fly   177 CWMNFQKFPFDQQFCSTVLESWMYNTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSD 241
            |::....||.|:..|.....|:.|..:::...|          :.|..|....::|.   :.|..
Zfish   179 CYLKLHNFPMDEHSCPLEFSSYGYPKNEIQYRW----------QRRSVEVADQRYWR---LYQFA 230

  Fly   242 GDNLRHGAFAGNYSSLSFTV-----NLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIM 301
            ...||:.:...|..|..:.|     :|.|.:|::.:..|:|..|||.:||||||:..||.|.|..
Zfish   231 FVGLRNSSDVANTQSGEYVVMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPARTS 295

  Fly   302 LGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKV 366
            ||.:|:|:..|||:...|:||||||:...:::...|..|.|.:|:|:..::.....::|   ||.
Zfish   296 LGITTVLTMTTLSTISRKSLPKVSYVTAMDLFVSVCFIFTFAALMEYGTLHYFTSNRQN---KKT 357

  Fly   367 NSKYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPN 431
            .|.:..|.::.                                ::|.|...:.  .||....|.:
Zfish   358 KSSHAQKPSMV--------------------------------NIRPGTSLLQ--MNNIAPYHED 388

  Fly   432 LPIIRTECAEA-DTVSI------CSA---RTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRR 486
             .....||.:. |..|.      |.:   |.|..| |.|.|                    ||..
Zfish   389 -DDYAYECLDGKDCTSFFCCFDDCRSGAWRENRMH-VHVSK--------------------IDSY 431

  Fly   487 SRFLFPAMFLAFNALYWT-FVYV 508
            ||..||..|..||.:||. ::|:
Zfish   432 SRIFFPTAFGLFNLVYWIGYLYL 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	117/481 (24%)
gabrg1	XP_009305483.1	LIC	58..451	CDD:455710	116/477 (24%)
		LGIC_ECD_GABAAR_G	79..260	CDD:349801	40/199 (20%)
		Cys-loop	179..193	CDD:349801	4/13 (31%)